经导管主动脉瓣置换术治疗二叶式主动脉瓣狭窄的现状及展望  

Transcatheter aortic valve replacement for bicuspid aortic valve stenosis

作　　者：胡泼[1] 王力涵[1] 刘先宝[1] 王建安[1] HU Po;WANG Lihan;LIU Xianbao;WANG Jian'an(Department of Cardiology,the Second Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 310009,China)

机构地区：[1]浙江大学医学院附属第二医院心内科,杭州310009

出　　处：《心电与循环》2022年第1期1-5,18,共6页Journal of Electrocardiology and Circulation

摘　　要：主动脉瓣二叶式畸形(BAV)由于其特殊的解剖结构对于经导管主动脉瓣置换术(TAVR)而言是一个技术难题。尽管BAV被排除在关于TAVR的随机对照研究之外,但临床实践中仍有部分患者接受了TAVR治疗。多中心注册研究证实了TAVR应用于BAV患者的临床结局与常规三叶式主动脉瓣(TAV)患者类似。本文系统回顾关于TAVR应用于BAV患者的相关临床研究,讨论BAV患者的手术策略及风险预防,旨在促进TAVR在BAV患者中更好地推广应用。Bicuspid aortic valve(BAV)represents a complex anatomic scenario for transcatheter aortic valve replacement(TAVR)because of its unique technical challenges.Despite exclusion of BAV from the randomized trials,an increasing number of patients with BAV-aortic stenosis have been treated with TAVR.Contemporary multicenter registry-based studies indicate that patients undergoing TAVI for BAV have similar outcomes as those with tricuspid aortic valve stenosis.In this review article,we provide a thorough overview of the available clinical data regarding the outcomes of TAVR in BAV,as well as important topics regarding prosthesis size selection,prosthesis type selection、coronary risk and cerebral embolic protection.

关 键 词：经导管主动脉瓣置换术 主动脉瓣狭窄 主动脉瓣二叶式畸形 

分 类 号：R654.2[医药卫生—外科学]