心脏磁共振组织追踪技术在评估扩张型心肌病患者左心室心肌应变中的价值  

The validity of cardiovascular magnetic resonance tissue tracking in evaluation of left ventricular myocardial strain in patients with dilated cardiomyopathy

作　　者：徐洪高[1] 迟文 孙建忠[2] XU Honggao;CHI Wen;SUN Jianzhong(Department of Radiology,the First People's Hospital of Yuhang,Hangzhou 311100,China;不详)

机构地区：[1]杭州市余杭区第一人民医院放射科,311100 [2]浙江大学附属第二医院放射科

出　　处：《心电与循环》2022年第1期70-73,共4页Journal of Electrocardiology and Circulation

摘　　要：目的探讨心脏磁共振组织追踪技术(CMRTT)在评估扩张型心肌病(DCM)患者左心室心肌应变中的价值。方法选择2018年3月至2021年1月杭州市余杭区第一人民医院收治的DCM患者52例,同期30例健康体检者作为对照组。均行CMRTT检查并测定左心室射血分数(LVEF)、整体纵向应变峰值(GPLS)、整体环向应变峰值(GPCS)和整体径向应变峰值(GPRS),检测血浆氨基末端脑钠肽前体(NT-pro BNP)。DCM患者分为LVEF≤50%组(28例)和LVEF>50%组(24例)。比较LVEF≤50%组、LVEF>50%组及对照组左心室心肌应变参数和血浆NT-pro BNP水平的差异。结果DCM患者血浆NT-pro BNP水平明显高于对照组,LVEF≤50%组血浆NT-pro BNP水平明显高于LVEF>50%组,差异均有统计学意义(均P<0.05);LVEF≤50%组左心室GPLS、GPCS、GPRS绝对值均低于LVEF>50%组和对照组,差异均有统计学意义(均P<0.05);LVEF>50%组左心室GPLS、GPCS、GPRS绝对值明显低于对照组,差异均有统计学意义(均P<0.05);DCM患者GPLS、GPCS和GPRS绝对值与血浆NT-pro BNP水平均呈负相关(r=-0.873、-0.842、-0.811,均P<0.05),与LVEF均呈正相关(r=0.893,0.839,0.857,均P<0.05)。结论CMRTT可用于评估DCM患者左心室心肌功能。Objective To determine the validity of cardiovascular magnetic resonance tissue tracking(CMRTT)in evaluation of left ventricular myocardial strain in patients with dilated cardiomyopathy(DCM).Methods Fifty-two patients with DCM were selected and 30 healthy subjects served as a control group in the First People's Hospital of Yuhang from March 2018 to January 2021.CMRTT was performed and left ventricular ejection fraction(LVEF),global peak longitudinal strain(GPLS),global peak circumferential strain(GPCS)and global peak radial strain(GPRS)were measured.Plasma NT-pro BNP was measured.DCM patients were divided into LVEF≤50%group(n=28)and LVEF>50%group(n=24).The left ventricular myocardial strain parameters and plasma NT-pro BNP were compared between LVEF≤50%group,LVEF>50%group and control group.Results The plasma NT-pro BNP was significantly higher in DCM patients than in the control group,and was significantly higher in LVEF≤50%group than in LVEF>50%group(all P<0.05).The absolute values of GPLS,GPCS and GPRS in LVEF≤50%group were significantly lower than those in LVEF>50%group and control group(all P<0.05).The absolute values of GPLS,GPCS and GPRS in LVEF>50%group were significantly lower than those in control group(all P<0.05).GPLS,GPCS and GPRS were negatively correlated with plasma NT-pro BNP(r=-0.873,-0.842,-0.811,all P<0.05)and positively correlated with LVEF(r=0.893,0.839,0.857,all P<0.05)in patients with DCM.Conclusion CMRTT may be used to evaluate left ventricular myocardial function in patients with DCM.

关 键 词：扩张型心肌病 心脏磁共振组织追踪技术 心肌应变 氨基末端脑钠肽前体 

分 类 号：R542.2[医药卫生—心血管疾病]