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作 者:邓瑞芬[1] 白勇涛 罗笑婵 王娜[1] 于利平 杨军 李颖隽 石涛 邢小燕[1] 张波[1] 李世蕊[1] 卜石[1] DENG Ruifen;BAI Yongtao;LUO Xiaochan;WANG Na;YU Liping;YANG Jun;LI Yingjuan;SHI Tao;XING Xiaoyan;ZHANG Bo;LI Shirui;BU Shi(Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China;Department of General Family Medicine, Taiyanggong Community Health Service Center, Chaoyang District, Beijing 100028, China;Department of General Family Medicine, Xiangheyuan Community Health Service Center, Chaoyang District, Beijing 100028, China)
机构地区:[1]中日友好医院内分泌科,北京100029 [2]北京市朝阳区太阳宫社区卫生服务中心全科医学科,北京100028 [3]北京市朝阳区香河园社区卫生服务中心全科医学科,北京100028
出 处:《中国骨质疏松杂志》2022年第2期276-279,284,共5页Chinese Journal of Osteoporosis
基 金:中日友好医院院级课题面上项目(2016-1-MS-4);北京市朝阳区科学技术委员会社会发展计划(CYSF1524)。
摘 要:目的了解北京社区绝经后女性骨折发生情况,探讨骨质疏松性骨折二级预防策略。方法选取2016年3月至2017年11月就诊于北京市朝阳区太阳宫社区卫生服务中心和香河园社区卫生服务中心的绝经后女性,共2866人。填写自行设计的骨质疏松症危险因素调查问卷,了解受访者骨折发生的类型(暴力性或非暴力性)、部位和发生年龄。分析女性一生中不同年龄段骨折发生的特点。结果受访的绝经后女性平均年龄(62.39±6.94)岁,受访的2866人中有635人(19.61%)在受访时至少已有一次骨折史,其中有73人(2.54%)发生了两次或两次以上骨折。58.64%的暴力性骨折发生在绝经前,80%的脆性骨折发生在绝经后,这两种类型骨折发生的年龄具有显著统计学差异。在所有的典型部位脆性骨折当中,前臂远端骨折占比最大,为50.43%,发生的平均年龄为(56.0±11.76)岁;髋部骨折发生占比8.33%,平均发生年龄为(59.8±12.69)岁。结论女性绝经后发生的骨折主要是脆性骨折,其中前臂远端脆性骨折较髋部脆性骨折至少早3年发生。加强对已发生前臂远端脆性骨折的绝经后女性的管理,对预防再发骨质疏松性骨折(尤其是髋部骨折)的效益较大。Objective To understand the incidence of fractures in postmenopausal women in Beijing communities,and to explore secondary prevention strategies for osteoporotic-fracture.Methods We got the information about risk factors of osteoporosis,age and circumstances when fractures occurred by a questionnaire-based-survey from 2866 postmenopausal women in Beijing Taiyanggong Community Health Service Center and Beijing Xiangheyuan Community Health Service Center from March 2016 to November 2017.And analyzed the characteristics of fractures at different ages in women's life.Results The average age of postmenopausal women interviewed was 62.39±6.94 years old.Among the 2866 women interviewed,635(19.61%)had at least one fracture history at the time of the interview,of whom 73(2.54%)had experienced two or more fractures.58.64%of traumatic fractures occurred before menopause,and 80%of fragility fractures occurred after menopause.The age at which these two types of fractures occurred was significantly different.Among all typical fragility fractures,distal forearm fractures accounted for the largest proportion(50.43%),and the average age of occurrence was 56.0±11.76 years.Hip fractures accounted for 8.33%,and the average age of occurrence was 59.8±12.69 years.Conclusion Fractures that occur after menopause in women are mainly fragility fractures,and distal forearm fragility fractures occur at least 3.8 years earlier than hip fragility fractures.Evaluation of the fracture risk of postmenopausal women who have experienced distal forearm fragility fractures and start proper anti-osteoporotic treatment have the greater effectiveness-cost ratio in preventing subsequent osteoporotic fractures,especially hip fractures.
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