体外膈肌起搏器联合吞咽训练治疗重症消化道肿瘤化疗后呃逆患者吸入性肺炎的临床效果  

Clinical effect of external diaphragm pacemaker combined with swallowing training in the treatment of aspiration pneumonia in patients with hiccup after chemotherapy for severe gastrointestinal tumor

作　　者：徐海燕 陈霞霞 魏亚玲[1] 王丽萍[1] 吴珺 杨敏[1] 李洋娟 XU Haiyan;CHEN Xiaxia;WEI Yaling;WANG Liping;WU Jun;YANG Min;LI Yangjuan(No.4 Ward of General Surgery Department,Lanzhou University Second Hospital,Lanzhou 730030,China)

机构地区：[1]兰州大学第二医院普通外科四病区,甘肃兰州730030

出　　处：《临床医学研究与实践》2022年第6期85-88,共4页Clinical Research and Practice

摘　　要：目的观察体外膈肌起搏器(EDP)联合吞咽训练治疗重症消化道肿瘤化疗后呃逆患者吸入性肺炎的临床效果。方法按随机数字表法将65例重症消化道肿瘤化疗后出现呃逆继发吸入性肺炎的患者分为对照组(33例)和治疗组(32例)。对照组给予基础治疗+吞咽训练,治疗组给予基础治疗+吞咽训练+EDP。观察患者的痰液细菌学培养检出结果,比较两组患者的临床疗效及临床相关指标改善时间。结果 65例患者的痰细菌学培养中共检出了112株病原菌,其中革兰氏阴性菌有85株,占75.89%;革兰氏阳性菌有27株,占24.11%。治疗组的疗效显著率和治疗总有效率均高于对照组(P<0.05)。治疗组的体温恢复正常时间、白细胞计数恢复正常时间、肺部啰音消失时间、胸部CT炎症吸收时间、痰培养转阴时间、应用抗生素时间均短于对照组(P<0.001)。结论重症消化道肿瘤化疗后呃逆患者吸入性肺炎的病原菌多为革兰氏阴性菌,EDP联合吞咽训练治疗该患者的效果显著。Objective To observe the clinical effect of external diaphragm pacemaker(EDP) combined with swallowing training in the treatment of aspiration pneumonia in patients with hiccup after chemotherapy for severe gastrointestinal tumor.Methods A total of 65 patients with hiccup secondary to aspiration pneumonia after chemotherapy for severe gastrointestinal tumors were divided into control group(33 cases) and treatment group(32 cases) according to random number table method.The control group was given basic treatment + swallowing training,and the treatment group was given basic treatment + swallowing training + EDP.The results of sputum bacteriological culture were observed,and the clinical efficacy and improvement time of clinical related indexes of the two groups were compared.Results A total of112 strains of pathogens were detected in sputum bacteriological culture of 65 patients,including 85 strains of Gram-negative bacteria,accounting for 75.89%,and 27 strains of Gram-positive bacteria,accounting for 24.11%.The significant rate of curative effect and total effective rate of treatment in the treatment group were higher than those in the control group(P<0.05).The recovery time of body temperature,recovery time of leukocyte count,disappearance time of pulmonary rale,absorption time of chest CT inflammation,negative time of sputum culture and application time of antibiotics in the treatment group were shorter than those in the control group(P <0.001).Conclustion Most of the pathogens of aspiration pneumonia in patients with hiccup after chemotherapy for severe gastrointestinal tumor are Gramnegative bacteria.EDP combined with swallowing training has a significant effect on these patients.

关 键 词：体外膈肌起搏器 吞咽训练 重症消化道肿瘤 化疗 呃逆 吸入性肺炎 

分 类 号：R565.4[医药卫生—呼吸系统]