升陷通脉汤治疗老年冠心病患者的临床效果  

Clinical effect of Shengxian Tongmai decoction in the treatment of elderly patients with coronary heart disease

作　　者：赵丽[1] 王小姝 ZHAO Li;WANG Xiaoshu(Traditional Chinese Medicine Hospital of Baoji,Baoji 721001,China)

机构地区：[1]宝鸡市中医医院,陕西宝鸡721001

出　　处：《临床医学研究与实践》2022年第6期149-153,共5页Clinical Research and Practice

摘　　要：目的探讨升陷通脉汤治疗老年冠心病患者的临床效果。方法选取2020年4月至2021年5月我院收治的86例老年冠心病的患者作为研究对象,将其随机分为对照组(43例,丹参注射液治疗)及观察组(43例,升陷通脉汤治疗)。比较两组患者的临床效果。结果观察组的治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的LVESD、LVEDD及LVMI均降低,LVEF、CI及SI均升高,且观察组优于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的心绞痛发作次数及持续时间均改善,且观察组优于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的全血高切黏度、全血低切黏度、血浆黏度及纤维蛋白原水平均降低,且观察组低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的HDL-C水平升高,TC、TG水平降低,且观察组优于对照组(P<0.05)。治疗后,两组的SOD、MDA及MPO水平均改善,且观察组优于对照组(P<0.05)。治疗后,两组的SAQ、GQOLI-74评分均升高,且观察组高于对照组(P<0.05)。两组的药物不良反应总发生率比较,差异无统计学意义(P>0.05)。结论升陷通脉汤治疗老年冠心病患者的效果显著,可提高患者的心功能,改善心绞痛发作情况及血液流变学指标,降低血脂水平及氧化应激反应指标水平,改善生活质量,值得临床推广应用。Objective To ex plore the clinical effect of Shengxian Tongmai decoction in the treatment of elderly patients with coronary heart disease.Methods A total of 86 elderly patients with coronary heart disease treated in our hospital from April 2020 to May 2021 were selected as the research objects.The patients were randomly divided into control group(43 cases,treated with Danshen injection) and observation group(43 cases,treated with Shengxian Tongmai decoction).The clinical effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the LVESD,LVEDD and LVMI in the two groups decreased,LVEF,CI and SI increased,and those in the observation group were better than the control group,and the differences were statistically significant(P <0.05).After treatment,the frequency and duration of angina pectoris in the two groups improved,and those in the observation group were better than the control group,and the differences were statistically significant(P<0.05).After treatment,the whole blood viscosity high shear,whole blood viscosity low shear,plasma viscosity and fibrinogen level in the two groups decreased,and those in the observation group were lower than the control group,and the differences were statistically significant(P<0.05).After treatment,the level of HDL-C increased and the levels of TC and TG decreased in the two groups,and those in the observation group were better than the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of SOD,MDA and MPO in the two groups improved,and those in the observation group were better than the control group(P<0.05).After treatment,the scores of SAQ and GQOLI-74 in the two groups increased,and those in the observation group were higher than the control group(P <0.05).There was no significant difference in the total incidence of adverse drug reactions between the two group

关 键 词：升陷通脉汤 冠心病 心绞痛 血脂水平 氧化应激反应 

分 类 号：R541.4[医药卫生—心血管疾病]