慢性疲劳综合征诊断标志物的研究进展  

Research Progress of Diagnostic Markers for Chronic Fatigue Syndrome

作　　者：何俊彦 涂小雨 陈泉 李柏 HE Junyan;TU Xiaoyu;CHEN Quan;LI Bai(School of Traditional Chinese Medicine,Naval Medical University,Shanghai 200433,China;Department of Rehabilitation Medicine and Physiotherapy,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学中医系,上海200433 [2]海军军医大学第一附属医院康复医学与理疗科,上海200433

出　　处：《医学综述》2022年第3期569-573,共5页Medical Recapitulate

基　　金：上海市进一步加快中医药事业发展三年行动计划(2018年-2020年)(ZY(2018-2020)-FWTX-8007)。

摘　　要：慢性疲劳综合征(CFS)以至少6个月以上致残性疲劳为特征,并伴有其他精神、躯体症状。临床上CFS主要通过疲劳等主观症状进行诊断,而对于其病理机制和治疗效果的评估则需要精确的客观标志物来验证。可靠的诊断标志物可以为CFS临床诊断提供可重复、简便、科学的依据,但由于CFS疾病本身的复杂性,目前尚无明确的诊断标志物可作为诊断的金标准。近年来,随着免疫学和微生物学研究的发展,CFS的诊断逐渐客观化。未来CFS的诊断、治疗将更加快捷、精确。Chronic fatigue syndrome(CFS)is characterized by disabling fatigue for at least 6 months with other mental and physical symptoms.Clinical diagnosis of CFS is mainly based on subjective symptoms such as fatigue,while the assessment of its pathological mechanism and therapeutic effect needs to be validated by accurate objective markers.Reliable diagnostic markers can provide repeatable,simple and scientific basis for the clinical diagnosis of CFS.However,due to the complexity of CFS,there is no clear diagnostic markers that can be used as a gold standard for diagnosis at present.Recent advances in immunology and microbiology have promoted the objectification of CFS diagnosis,so the diagnosis and treatment of CFS will be faster and more accurate in the future.

关 键 词：慢性疲劳综合征 肌痛性脑脊髓炎 诊断标志物 

分 类 号：R442.8[医药卫生—诊断学]