3C胰岛素泵对老年1型糖尿病患者血糖调节的临床分析  

Clinical Analysis of 3C Insulin Pump on Blood Glucose Regulation in Elderly Patients with Type 1 Diabetes

作　　者：黄彬清 黄宏[1] 邓玲[1] 苏小燕 林佳清 HUANG Binqing;HUANG Hong;DENG Ling;SU Xiaoyan;LIN Jiaqing(Department of Endocrinology,Fujian Provincial Hospital,Fuzhou,Fujian Province,350001 China)

机构地区：[1]福建省立医院内分泌科,福建福州350001

出　　处：《糖尿病新世界》2021年第24期94-96,100,共4页Diabetes New World Magazine

摘　　要：目的探究3C胰岛素泵对老年1型糖尿病患者血糖调节的效果及安全性的影响。方法选取2018年1月—2021年1月老年1型糖尿病患者100例为该次研究对象,计算机随机化法分组,对照组实施动态血糖监测与胰岛素泵联合干预,研究组应用3C胰岛素泵干预,对两组老年1型糖尿病患者血糖调节结果进行分析。结果两组老年1型糖尿病患者治疗后的HbA1c、FPG、2 hPG、TNF-α、IL-6、hs-CRP水平均低于治疗前,差异有统计学意义(P<0.05);研究组治疗后HbA1c、FPG、2 hPG水平、血糖达标天数、低血糖发生次数、TNF-α、IL-6、hs-CRP血清炎症因子均低于对照组,差异有统计学意义(P<0.05);两组治疗后空腹胰岛素、餐后2 h胰岛素水平,空腹、餐后1 h、2 h的C肽/血糖水平均高于治疗前,差异有统计学意义(P<0.05);研究组治疗后空腹胰岛素、餐后2 h胰岛素水平、空腹、餐后1 h、2 h的C肽/血糖水平高于对照组,差异有统计学意义(P<0.05)。结论老年1型糖尿病患者接受3C胰岛素泵干预,可更好改善其血糖、胰岛素、炎症因子指标水平、C肽/血糖值,缩短血糖控制的时间,且可降低低血糖的发生次数,安全有效。Objective To explore the effect of 3C insulin pump on blood glucose regulation and safety in elderly patients with type 1 diabetes.Methods A total of 100 elderly patients with type 1 diabetes from January 2018 to January 2021 were selected as the subjects of the study,and they were grouped by computer randomization.The control group implemented dynamic blood glucose monitoring combined with insulin pump intervention,and the study group used 3C insulin pump intervention.The results of blood glucose regulation in two groups of elderly patients with type 1 diabetes were analyzed.Results The levels of HbA1c,FPG,2 hPG,TNF-α,IL-6,and hs-CRP after treatment in the two groups of elderly patients with type 1 diabetes were lower than before treatment,and the difference was statistically significant(P<0.05).After treatment,the levels of HbA1c,FPG,2 hPG in the study group,the number of days of blood glucose reaching the standard,the number of hypoglycemia,the serum inflammatory factors of TNF-α,IL-6,hs-CRP factors of in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05).The levels of fasting insulin and 2 h postprandial insulin levels after treatment,and C-peptide/blood glucose levels at fasting,1 h and 2 h postprandial were higher in the two groups than before treatment,and the difference was statistically significant(P<0.05).The fasting insulin after treatment,2 h postprandial insulin levels,fasting,1 h and 2 h postprandial C-peptide/glycemia levels in the study group were higher than those of the control group,the difference was statistically significant(P<0.05).Conclusion Elderly type 1 diabetes patients receiving 3C insulin pump intervention can better improve their blood sugar,insulin,inflammatory factor index levels,C peptide/blood glucose value,and shorten the time of blood glucose control,and can reduce the occurrence of hypoglycemia,being safe and effective.

关 键 词：3C胰岛素泵 老年患者 1型糖尿病 血糖调节 

分 类 号：R587.1[医药卫生—内分泌]