上海闵行区某医疗机构金黄色葡萄球菌污染及耐药性分析  

Contamination and drug resistance analysis of Staphylococcus aureus in a medical institution in Minhang District,Shanghai

作　　者：汪静 王小光[1] 汪琦 何樱瑛 WANG Jing;WANG Xiao-guang;WANG Qi;HE Ying-ying(Minhang District Center for Disease Control and Prevention,Shanghai 201101,China)

机构地区：[1]上海市闵行区疾病预防控制中心,上海201101

出　　处：《中国卫生检验杂志》2022年第1期109-111,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的分析上海闵行区某医疗机构金黄色葡萄球菌污染分布情况及耐药性。方法收集上海闵行区某医院2017年—2020年每季度重点科室物体表面和医护人员手样品,同时每季度收集医院金黄色葡萄球菌感染者分离菌株。通过肉汤稀释法测定金黄色葡萄球菌耐药性,分析金黄色葡萄球菌分布情况和耐药性。结果 729份环境样本中,检出金黄色葡萄球菌26株,检出率为3.6%。涉及诊疗物品13类,检出率高的为病号服和袖口(15.4%)。涉及到3个重点科室,检出率分别为呼吸内科10.4%、神经外科5.0%、ICU 1.4%。对环境消毒效果分析显示含氯消毒剂有效率为99.2%,乙醇有效率为96.2%。金黄色葡萄球菌对青霉素类药物耐药性最强,高达100.0%(26/26)。结论医院环境存在金黄色葡萄球菌的污染,并呈现多重耐药,应加强医院环境监测,严格控制院内感染的发生与流行。Objective This paper is to analyze the distribution of contamination and drug resistance ofStaphylococcus aureusin a medical institution in Minhang District, Shanghai.Methods Samples of surface objects and hands of medical staff were collected from key departments of a hospital in Minhang District every quarter from 2017 to 2020. At the same time, isolates ofStaphylococcus aureusfrom hospital infections were collected quarterly. The drug resistance ofStaphylococcus aureuswas determined by broth dilution method to analyze the distribution and drug resistance ofStaphylococcus aureus.Results Among 729 environmental samples, 26 strains ofStaphylococcus aureuswere detected, and the detection rate was 3. 6%. 13 categories of diagnostic and treatment items were involved, and the high detection rates were hospital gown and cuffs(15. 4%). The detection rate was 10. 4% in respiratory medicine department, 5. 0% in neurosurgery department and 1. 4% in ICU department. The analysis of environmental disinfection effect showed that the effective rate of chlorine-containing disinfectant was 99. 2%, and that of ethanol was 96. 2%.Staphylococcus aureushad the highest resistance to penicillin(100. 0%)(26/26).Conclusion Staphylococcus aureuscontamination exists in hospital environment and multiple drug resistance is presented. It is necessary to strengthen hospital environmental monitoring and strictly control the occurrence and prevalence of nosocomial infection.

关 键 词：金黄色葡萄球菌 医院 污染情况 

分 类 号：R446.5[医药卫生—诊断学]