Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern  

作　　者：Jingwen Ai Haocheng Zhang Qiran Zhang Yi Zhang Ke Lin Zhangfan Fu Jieyu Song Yuanhan Zhao Mingxiang Fan Hongyu Wang Chao Qiu Yang Zhou Wenhong Zhang 

机构地区：[1]Department of Infectious Diseases,National Medical Center for Infectious Diseases,Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response,Huashan Hospital,Shanghai Medical College,Fudan University,Shanghai,China [2]National Clinical Research Center for Aging and Medicine,Huashan Hospital,Fudan University,Shanghai,China [3]Key Laboratory of Medical Molecular Virology(MOE/MOH)Shanghai Medical College,Fudan University,Shanghai,China

出　　处：《Cell Research》2022年第1期103-106,共4页细胞研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(82041010);the Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response(20dz2260100);the Key Discipline Construction Plan from Shanghai Municipal Health Commission(GWV-10.1-XK01).

摘　　要：Dear Editor,As of October,2021,SARS-CoV-2 has infected more than 230 million people;promoting roll-out vaccinations could help build herd immunity for the pandemic.However,the waning of antibody in magnitude and decreased protective efficacy in multiple types of vaccines have been reported.

关 键 词：RBD protective neutral 

分 类 号：R186[医药卫生—流行病学]