温肺止流丹加减内服联合苍耳子散熏蒸治疗肺气虚寒型变应性鼻炎的临床研究  

Clinical Study of Oral Use of Modified Wenfei Zhiliu Pills Combined with Fructus Xanthii Powder Fumigation in the Treatment of Allergic Rhinitis of Lung-qi Deficiency-cold Syndrome

作　　者：叶健如 陈文勇[2] YE Jian-Ru;CHEN Wen-Yong(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510120 Guangdong,China)

机构地区：[1]广州中医药大学第二临床医学院,广东广州510405 [2]广东省中医院,广东广州510120

出　　处：《广州中医药大学学报》2022年第2期312-317,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医院“中医优势病种”突破专项(编号:202037)。

摘　　要：【目的】观察温肺止流丹加减内服联合苍耳子散熏蒸治疗肺气虚寒型变应性鼻炎患者的临床疗效。【方法】将70例肺气虚寒型变应性鼻炎患者随机分为试验组和对照组,每组各35例。对照组给予温肺止流丹加减内服治疗,试验组给予温肺止流丹加减内服联合苍耳子散熏蒸治疗,疗程为7 d。观察2组治疗前后鼻部症状(鼻塞、鼻痒、喷嚏、流涕),眼部症状(眼痒/异物感/眼红、流泪)和体征评分及症状体征总分的变化情况,并评价2组患者的临床疗效和安全性。【结果】(1)治疗7 d后,试验组的总有效率为82.86%(29/35),对照组为42.86%(15/35),组间比较,试验组的临床疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的鼻塞、鼻痒、喷嚏、流涕等鼻部症状评分,眼痒/异物感/眼红、流泪等眼部症状评分和体征评分及症状体征总分均较治疗前明显改善(P<0.01),且试验组对鼻塞、鼻痒、喷嚏、流涕等鼻部症状评分及症状体征总分的改善作用均明显优于对照组,差异均有统计学意义(P<0.05或P<0.01),而2组治疗后的眼部症状评分和体征评分比较,差异均无统计学意义(P>0.05)。(3)治疗过程中,2组患者均未出现明显的不良反应。【结论】温肺止流丹加减内服联合苍耳子散熏蒸治疗肺气虚寒型变应性鼻炎患者疗效确切,其疗效优于单纯温肺止流丹加减内服。Objective To observe the clinical efficacy of modified Wenfei Zhiliu Pills(a herbal compound prescription mainly with the action of treating rhinitis with lung yang deficiency pattern)for oral use combined with Fructus Xanthii Powder fumigation in treating allergic rhinitis of lung-qi deficiency-cold syndrome. Methods Seventy allergic rhinitis patients with lung-qi deficiency-cold syndrome were randomly divided into the trial group and the control group,with 35 cases in each group. The control group was given oral use of modified Wenfei Zhiliu Pills,the trial group was given oral use of modified Wenfei Zhiliu Pills combined with Fructus Xanthii Powder fumigation,and the course of treatment lasted 7 days. The changes of nasal symptoms(nasal obstruction,nasal itching, sneezing and runny nose), ocular symptoms(itching of the eye, foreign body sensation in the eye,conjunctival congestion and tearing),signs scores,and total symptom and sign scores were observed in the two groups before and after treatment. After treatment,the clinical efficacy and safety of the two groups were evaluated.Results(1)After 7 days of treatment,the total effective rate of the trial group was 82.86%(29/35)and that of the control group was 42.86%(15/35). The intergroup comparison showed that the clinical efficacy of the trial group was significantly superior to that of the control group,and the difference was statistically significant(P<0.05).(2)After treatment, scores of nasal symptoms such as nasal obstruction, nasal itching, sneezing and runny nose,and scores of ocular symptoms such as itching of the eye,foreign body sensation in the eye,conjunctival congestion and tearing,as well as the total scores of the symptoms and signs in the two groups were significantly improved compared with those before treatment(P<0.01). The effect on improving symptoms of obstruction,nasal itching, sneezing and runny nose as well as the total scores of the symptoms and signs in the trial group was significantly superior to that in the control group,and the dif

关 键 词：变应性鼻炎 肺气虚寒型 温肺止流丹 苍耳子散 熏蒸 

分 类 号：R276.1[医药卫生—中医五官科学] R766.3[医药卫生—中医学]