经胸微创封堵术与传统体外循环手术在治疗室间隔缺损中的效果和安全性对比评价  

Comparative Evaluation of the Effect and Safety of Transthoracic Minimally Invasive Occlusion and Traditional Cardiopulmonary Bypass Surgery in the Treatment of Ventricular Septal Defect

作　　者：虞华 YU Hua(Department of Cardiothoracic Surgery,Guiyang Maternal and Child Health Hospital,Guiyang,Guizhou Province,550000 China)

机构地区：[1]贵阳市妇幼保健院心胸外科,贵州贵阳550000

出　　处：《系统医学》2021年第24期21-25,共5页Systems Medicine

基　　金：国家科学基金委员会资助项目(2012049)。

摘　　要：目的分析研究经胸微创封堵术与传统体外循环手术在治疗室间隔缺损中的效果和安全性。方法选取该院2013年5月—2018年6月收治的室间隔缺损患者200例作为研究对象,随机分为两组,对照组和观察组各100例,观察组采用经胸微创封堵术,对照组实施传统体外循环手术,观察并比较两组患者的治疗效果、并发症发生率、生活质量、临床指标。结果观察组的治疗总有效率(99%)高于对照组(92%),差异有统计学意义(χ^(2)=5.701,P<0.05)。观察组并发症发生率低于对照组(50%vs 70%),差异有统计学意义(χ^(2)=8.333,P=0.003)。观察组生活质量评分(91.31±5.39)分、(91.30±5.22)分、(89.99±3.12)分、(94.51±3.38)分、(95.21±2.54)分高于对照组的(81.26±5.37)分、(80.68±5.44)分、(81.64±3.29)分、(83.66±4.59)分、(89.11±3.22)分,差异有统计学意义(P<0.05)。观察组手术时间(74.29±12.57)min、机械通气时间(5.15±0.59)h、下床时间(4.59±1.03)d、住院时间(7.82±1.57)d显著优于对照组的(133.65±15.28)min、(19.26±2.57)d、(7.93±1.25)d、(12.69±2.04)d,差异有统计学意义(P<0.05)。结论采用经胸微创封堵术中能够帮助患者提高治疗效率,减少患者并发症发生率,提高患者的生活质量,值得大力推广与应用。Objective To analyze and study the effect and safety of transthoracic minimally invasive occlusion and traditional cardiopulmonary bypass surgery in the treatment of ventricular septal defect. Methods 200 patients with ventricular septal defect admitted to the hospital from May 2013 to June 2018 were selected as the research objects.They were randomly divided into two groups, with 100 cases in each of the control group and the observation group.The observation group used transthoracic minimally invasive occlusion, and the control group performed traditional cardiopulmonary bypass surgery. Observed and compared the treatment effect, complication rate, quality of life, and clinical indicators of the two groups of patients. Results The total effective rate(99%) of the observation group was higher than that of the control group(92%), and the difference was statistically significant(χ^(2)=5.701, P<0.05). The incidence of complications in the observation group was lower than that in the control group(50% vs 70%), and the difference was statistically significant(χ^(2)=8.333,P=0.003). The quality of life score of the observation group was(91.31±5.39) points,(91.30 ±5.22) points,(89.99 ±3.12) points,(94.51 ±3.38) points,(95.21 ±2.54) points, higher than the control group(81.26 ±5.37)points,(80.68 ±5.44)points,(81.64±3.29)points,(83.66±4.59)points,(89.11±3.22)points, the difference was statistically significant(P<0.05).The clinical indicators operation time(74.29 ±12.57) min, mechanical ventilation time(5.15 ±0.59) h, bed time(4.59 ±1.03) d, and hospital stay(7.82 ±1.57) d of the observation group were significantly better than the control group(133.65±15.28) min,(19.26±2.57) h,(7.93±1.25) d,(12.69±2.04) d, the difference was statistically significant(P<0.05).Conclusion The use of minimally invasive transthoracic occlusion can help patients improve the efficiency of treatment,reduce the incidence of complications, and improve the quality of life of patients. It is worthy of vigorous promotion and applic

关 键 词：经胸微创封堵术 传统体外循环手术 室间隔缺损 临床效果 安全性 

分 类 号：R655[医药卫生—外科学]