糖尿病患者白内障术后后囊膜混浊的临床研究  

Clinical study of posterior capsular opacification after cataract surgery in diabetic patients

作　　者：李何欢 赵美玲[1] 高雪[3] 杨云鹏 刘文霞 姜霄晖[1] He-Huan Li;Mei-Ling Zhao;Xue Gao;Yun-Peng Yang;Wen-Xia Liu;Xiao-Hui Jiang(Qingdao Municipal Hospital Affiliated to Medical College of Qingdao University, Qingdao 266000, Shandong Province, China;Department of Ophthalmology, the People's Hospital of Jimo. Qingdao, Qingdao 266000, Shandong Province, China;Weifang Medical University, Weifang 261000, Shandong Province, China)

机构地区：[1]青岛大学医学院附属青岛市市立医院,中国山东省青岛市266000 [2]中国山东省青岛市即墨区人民医院眼科,266000 [3]潍坊医学院,中国山东省潍坊市261000

出　　处：《国际眼科杂志》2022年第3期457-461,共5页International Eye Science

摘　　要：目的:研究糖尿病患者白内障术后后囊膜混浊(PCO)的发生情况及其危险因素。方法:收集2016-04/08于我院行白内障超声乳化联合人工晶状体植入术的白内障患者182例203眼,根据术前是否合并糖尿病分为糖尿病组(DM组,98眼)和非糖尿病组(非DM组,105眼),DM组患者按照白内障术后30mo是否发生PCO分为PCO组(26眼)和非PCO组(72眼)。比较DM组和非DM组术后PCO的发生及分级情况,分析术前糖尿病病程、糖化血红蛋白(HbA1c)水平、是否存在糖尿病视网膜病变(DR)等因素对DM组患者白内障术后PCO发生影响。结果:术后12、18、24、30mo,DM组患者PCO发生率分别为10.2%、14.3%、22.4%、26.5%,非DM组患者分别为2.8%、4.8%、10.5%、14.3%,两组患者PCO程度均逐渐加重,且DM组患者各时间点PCO程度均重于非DM组,(均P<0.05)。PCO组和非PCO组患者术前糖尿病病程、存在DR情况均有差异(P<0.05),术前HbA1c水平无差异(P>0.05)。结论:糖尿病患者白内障术后PCO的发生率高于非糖尿病患者,且混浊程度较重,糖尿病患者术前糖尿病病程、存在DR是影响PCO发生的危险因素。AIM:To study the incidence and risk factors of posterior capsular opacification(PCO)after cataract surgery in diabetic patients.METHODS:Clinical data of 182 cases(203 eyes)who underwent cataract phacoemulsification combined with intracellular lens implantation in our hospital from April 2016 to August were collected.The patients were divided into diabetic group(DM group,98 eyes)and non-diabetic group(non-DM group,105 eyes)according to whether they had diabetes before operation.DM group were divided into groups according to whether PCO occurred 30mo after cataract surgery,26 eyes in the PCO group,and 72 eyes in non-PCO group.The incidence and grading of PCO in the DM group and the non-DM group were compared.The effects of preoperative diabetic course,HbA1c level and the presence of diabetic retinopathy on PCO in DM group were tested.RESULTS:The incidence of PCO was 10.2%,14.3%,22.4%,26.5%at 12,18,24 and 30mo in the DM group and 2.8%,4.8%,10.5%,and 14.3%in the non-DM group.Two groups of patients with the degree of PCO are gradually increasing,and the degree of each point in time the PCO patients with DM group were heavier than patients without DM group(all P<0.05).There were differences in the preoperative course of diabetes and the presence of DR between PCO and non-PCO groups(P<0.05),but there was no difference in the preoperative level of HbA1c(P>0.05).CONCLUSION:The incidence of PCO in diabetic patients after cataract surgery was higher than that in non-diabetic patients,and the degree of opacity was more severe.Preoperative course of diabetes and the presence of DR were risk factors for PCO.

关 键 词：后囊膜混浊 糖尿病 白内障 白内障超声乳化联合人工晶状体植入术 糖化血红蛋白 

分 类 号：R587.2[医药卫生—内分泌] R779.66[医药卫生—内科学]