机构地区:[1]Department of Rehabilitation Medicine,Dapeng New District Nan'ao People's Hospital,Shenzhen,Guangdong Province(518121),China [2]Department of Rehabilitation Medicine,Shenzhen Second People's Hospital,Shenzhen,Guangdong Province(518037),China [3]Department of Rehabilitation Medicine,Shenzhen Hospital of Guangzhou University of Chinese Medicine,Shenzhen,Guangdong Province(518034),China
出 处:《Chinese Journal of Integrative Medicine》2022年第2期106-115,共10页中国结合医学杂志(英文版)
基 金:the Medical and Health Research Fund Project of Medical and Health Group in Dapeng New District,Shenzhen,Guangdong,China(No.2019JTYM004)。
摘 要:Objective:To compare the clinical effects of interactive dynamic scalp acupuncture(IDSA),simple combination therapy(SCT),and traditional scalp acupuncture(TSA)on cognitive function,depression and anxiety in patients with post-stroke cognitive impairment.Methods:A total of 660 patients with post-stroke cognitive impairment who were admitted to 3 hospitals in Shenzhen City between May 2017 and May 2020 were recruited and randomly assigned to the IDSA(218 cases),SCT(222 cases)and TSA groups(220 cases)according to a random number table.All the patients received conventional drug therapy for cerebral stroke and exercise rehabilitation training.Scalp acupuncture and computer-based cognitive training(CBCT)were performed simultaneously in the IDSA group,but separately in the morning and in the afternoon in the SCT group.The patients in the TSA group underwent scalp acupuncture only.The course of treatment was 8 weeks.Before treatment(M0),1(M1)and 2 months(M2)after treatment,as well as follow-up at 1(M3)and 2 months(M4),the cognitive function of patients was assessed using the Mini-Mental State Examination(MMSE)and Montreal Cognitive Assessment Scale(MoCA)Scales;depression,anxiety,sleep quality,and self-care ability of patients were assessed using Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Rating Scale(HAMA),Pittsburgh Sleep Quality Index(PSQI),and Modified Barthel Index(MBI),respectively.During this trial,all adverse events(AEs)were accurately recorded.Results:There were no significant differences in the MMSE,MoCA,HAMD,HAMA,PSQI,and MBI scores among the 3 groups at M0(all P>0.05).In the IDSA group,the MMSE,MoCA and MBI scores from M2 to M4 were significantly higher than those in the SCT and TSA groups,while the HAMD,HAMA and PSQI scores were significantly reduced(all P<0.01).The changes of all above scores(M2–M0,M4–M0)were significantly superior to those in the SCT and TSA groups(all P<0.01,except M4–M0 of HAMD).At M2,the severity of MMSE,HAMD,HAMA,PSQI and MBI in the IDSA group was significantly lower
关 键 词:interactive dynamic scalp acupuncture stroke cognitive function DEPRESSION ANXIETY randomized controlled trial Chinese medicine
分 类 号:R246.6[医药卫生—针灸推拿学]
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