蝙蝠葛碱的药理作用研究进展  

Progress on Pharmacological Action of Dauriciny

作　　者：张冉冉 张菊 ZHANG Ran-ran;ZHANG Ju(College of Biological Science and Engineering,Hebei University of Economics and Business,Shijiazhuang 050061,China)

机构地区：[1]河北经贸大学生物科学与工程学院,河北石家庄050061

出　　处：《食品与药品》2022年第1期81-86,共6页Food and Drug

基　　金：河北省自然科学基金项目(编号:H2020207002);河北经贸大学科学研究与发展计划项目(编号:2021SGYB04)。

摘　　要：蝙蝠葛碱是由北豆根(蝙蝠葛)藤茎经提取分离而得的双苄基四氢异喹啉类生物碱。其具有相当广泛的药理学作用,主要具有抗肿瘤、抗心律失常、抗脑部缺血再灌注、抗心肌肥厚、消炎止痛及抗菌、抗阿尔茨海默病、抗血小板堆积、降血压、舒张平滑肌等作用。本文对蝙蝠葛碱的各项药理作用进行综述,以期为蝙蝠葛碱在临床治疗方面的深入研究提供一定的理论参考。Dauricine is a kind of bibenzyl tetrahydroisoquinoline alkaloid obtained by artificial extraction and separation from Menispermum dauricum.It has fairly broad pharmacological effects,including anti-tumor,anti-arrhythmia,anti-cerebral ischemia-reperfusion,anti-inflammatory and analgesic,anti-myocardial hypertrophy,anti-bacterial,anti-Alzheimer's disease,anti-platelet aggregation,anti-hypertensive,relaxing smooth muscle,and others.The pharmacological effects of dauricine are reviewed in this paper,in order to provide some theoretical reference for the further clinical study.

关 键 词：蝙蝠葛碱 药理作用 综述 

分 类 号：R285[医药卫生—中药学]