Nitrogenous Sesquiterpenoids from the South China Sea Nudibranch Hexabranchus sanguineus and Its Possible Sponge-Prey Acanthella cavernosa: Chiral Separation, Stereochemistry and Chemical Ecology  

作　　者：Shou-Mao Shen Zai-Yong Zhang Li-Gong Yao Jian-Rong Wang Yue-Wei Guo Xu-Wen Li 

机构地区：[1]State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China [2]School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China [3]Bohai rim Advanced Research Institute for Drug Discovery,198 Binhai East Road,High-tech Zone,Yantai,Shandong 264000,China

出　　处：《Chinese Journal of Chemistry》2022年第2期235-246,共12页中国化学（英文版）

基　　金：This research work was financially supported by the National Natural Science Foundation of China(Nos.81991521,82022069,42076099);the Shanghai Rising-Star Program(No.20QA1411100);"Youth Innovation Promotion Association"of Chinese Academy of Sciences(No.Y202065);the SKLDR/SIMM Project(No.SIMM2103ZZ-06).

摘　　要：A detailed chemical investigation of the South China Sea nudibranch Hexabranchus sanguineus,as well as its possible sponge-prey Acanthella cavernosa,led to the isolation of fifteen new nitrogenous sesquiterpenoids,namely ximaocavernosins A-0,including seven cadinanes(1-7),seven spiroaxanes(12-18)and one aromadendrane(19),together with thirteen known related compounds(8-11 and 20-28).

关 键 词：Hexabranchus sanguineus Acanthella cavernosa Chiral separation STEREOCHEMISTRY Chemical ecology 

分 类 号：O62[理学—有机化学]