重度脂血高速离心后对凝血指标的影响  

Effect of high-speed centrifugation of severe fatty blood on coagulation indexes

作　　者：施清蓉 宁长秀[2] SHI Qingrong;NING Changxiu(Department of Laboratory Medicine,Yichun Second People′s Hospital,Jiangxi Province,Yichun 336000,China;Department of Laboratory,the First People′s Hospital of Fuzhou,Jiangxi Province,Fuzhou 344000,China)

机构地区：[1]江西省宜春市第二人民医院检验科,江西宜春336000 [2]江西省抚州市第一人民医院检验科,江西抚州344000

出　　处：《中国当代医药》2022年第6期107-109,共3页China Modern Medicine

基　　金：江西省宜春市科技计划项目(JXYC2019KSC036)。

摘　　要：目的探讨高速离心后对于重度高血脂标本凝血指标检测结果的影响。方法选取2020年7月至2021年7月宜春市第二人民医院收治的85例患者作为研究对象,按照患者有无高脂血症将其分为观察组(43例)和对照组(42例),两组患者均使用16000 r/min的高速离心机对标本进行离心10、20、30 min,比较两组患者离心10、20、30 min后凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)水平。结果对照组患者标本经高速离心机离心10、20、30 min的APTT、PT、TT、FIB水平比较,差异无统计学意义(P>0.05)。研究组患者标本经高速离心机离心10、20、30 min的APTT、PT、TT、FIB水平比较,差异有统计学意义(P<0.05),离心20、30 min的APTT、PT、TT、FIB水平低于离心10 min,差异有统计学意义(P<0.05)。观察组患者标本经离心10、20 min后APTT、PT、TT、FIB水平高于对照组,差异有统计学意义(P<0.05)。两组患者间离心30 min后APTT、PT、TT、FIB水平比较,差异无统计学意义(P>0.05)。结论重度高血脂标本会影响凝血指标的测定,利用高速离心30 min可基本消除重度脂血对APTT、PT、TT、FIB测定的干扰,提高检测准确性。Objective To investigate the effect of high-speed centrifugation on the detection results of coagulation indexes of severe hyperlipidemia specimens.Methods A total of 85 patients admitted to Yichun Second People’s Hospital from July 2020 to July 2021 were selected as the research objects,and the patients were divided into observation group(43 cases)and control group(42 cases)based on the presence or absence of hyperlipidemia.Both groups of patients used a 16000r/min high-speed centrifuge to centrifuge the specimens for 10,20,and 30 min.The(activeated partial thromboplasting time,APTT),prothrombin time(PT),thrombin time(TT),and fipinogen(FIB)levels of the two groups of patients after centrifugation for 10,20 and 30 min were compared.Results After the specimens of the control group were centrifuged in a high-speed centrifuge for 10,20 and 30 min,the APTT,PT,TT,and FIB levels were compared at the three time points,and the differences were not statistically significant(P>0.05).After the specimens of the study group were centrifuged for 10,20 and 30 min,in a high-speed centrifuge,the APTT,PT,TT,and FIB levels were compared at the three time points,and the differences were statistically significant(P<0.05).Compared with centrifugation for 10 min,the levels of APTT,PT,TT,and FIB were significantly reduced after centrifugation for 20 and 30 min,and the differences were statistically significant(P<0.05).The levels of APTT,PT,TT,and FIB in the observation group after centrifugation for 10 min and 20 min were higher than those in the control group,and the differences were statistically significant(P<0.05).The differences were not statistically significant in the levels of APTT,PT,TT,and FIB between the two groups of patients after centrifugation for 30 min(P>0.05).Conclusion Severe hyperlipidemia specimens will affect the determination of coagulation indicators.Using high-speed centrifugation for 30 minutes can basically eliminate the interference of severe lipemia on the determination of APTT,PT,TT,and FIB,and improve th

关 键 词：高血脂 高速离心 凝血 检测 

分 类 号：R446[医药卫生—诊断学]