小儿败血症的诊断及生物标记物研究进展  

Research progress on the diagnosis and biomarkers of neonatal sepsis

作　　者：李敏 闵自立[1] LI Min;MIN Zili(Department of Neonatology,Yunnan Hospital for Maternal and Child Health,Yunnan,Kunming 650000,China)

机构地区：[1]云南省妇幼保健院新生儿科,昆明市650000

出　　处：《河北医药》2022年第1期124-128,共5页Hebei Medical Journal

摘　　要：新生儿败血症是由新生儿细菌性血流感染引起的一种临床疾病,是新生儿重症监护病房最严重的疾病之一。根据感染的病因分为早发性脓毒症和迟发性脓毒症,诊断主要依靠传统的微生物技术。新生儿败血症的临床并发症可能与支气管肺发育不良、动脉导管和坏死性小肠结肠炎有关。目前新生儿败血症的临床诊断和治疗手段非常有限。本文综述了新生儿败血症的认识、诊断和生物标记物的最新研究进展,旨在提高对新生儿败血症的认识,为临床提供最新诊断依据。Neonatal sepsis is a clinical disease caused by neonatal bacterial bloodstream infection,and it is one of the most serious diseases in neonatal intensive care unit(NICU).According to the etiology of infection,it can be divided into early-onset sepsis and late-onset sepsis,and its diagnosis mainly depends on traditional microbiology.The clinical complications of neonatal sepsis may be related to bronchopulmonary dysplasia,ductus arteriosus and necrotizing enterocolitis.At present,the clinical diagnosis and treatment ways of neonatal sepsis are very limited.This article reviews the latest research progress on the understanding,diagnosis and biomarkers of neonatal sepsis,in order to improve the understanding of neonatal septicemia and provide the latest diagnostic basis for clinical practice.

关 键 词：小儿败血症 诊断 生物标记物 

分 类 号：R725.153[医药卫生—儿科]