基于心脏磁共振测量的心外膜脂肪组织厚度与特发性右室流出道室性期前收缩射频消融效果的相关性研究  

Correlation Between the Thickness of Epicardial Adipose Tissue Measured by Cardiac Magnetic Resonance and Radiofrequency Ablation Effect of Idiopathic Right Ventricular Outflow Tract Premature Ventricular Contractions

作　　者：录志远 李黎[1] 白雪洋[1] 李宇娜 李中根 李凌[1] LU Zhiyuan;LI Li;BAI Xueyang;LI Yu’na;LI Zhonggen;LI Ling(Department of Cardiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院心血管内科,河南郑州450052

出　　处：《河南医学研究》2022年第4期583-587,共5页Henan Medical Research

摘　　要：目的研究基于心脏磁共振(CMR)测量的心外膜脂肪组织(EAT)厚度与特发性右室流出道室性期前收缩(ROVTPVCs)射频消融效果之间的相关性。方法回顾性分析2019年8月至2020年8月于郑州大学第一附属医院接受射频消融术的63名特发性RVOT-PVCs患者的相关资料。收集基线资料并进行术后随访,根据CMR图像资料测量局部EAT厚度,根据随访结果分为复发组和未复发组。比较两组间的差异。结果两组总手术时间、总射频消融时间比较,差异无统计学意义(P>0.05)。复发组右侧房室沟、前室间沟、右室游离壁的EAT厚度大于未复发组(P<0.05)。logistic回归分析显示右侧房室沟EAT厚度的增加是特发性RVOT-PVCs射频消融术后复发的独立危险因素,OR(95%CI)为1.618(1.055~2.483)。受试者工作特征(ROC)曲线显示预测特发性RVOT-PVCs射频消融术后复发的最佳截断值为右侧房室沟EAT厚度16.45mm(P=0.003),ROC曲线下面积(95%CI)为0.800(0.678~0.922)。结论EAT厚度增加特发性RVOT-PVCs射频消融术后患者的复发风险,是其独立的危险因素。Objective To study the correlation between the thickness of epicardial adipose tissue(EAT)measured by cardiac magnetic resonance(CMR)and radiofrequency ablation effect of idiopathic right ventricular outflow tract premature ventricular contractions(RVOT-PVCs).Methods A total of 63 patients with idiopathic RVOT-PVCs who underwent radiofrequency ablation in the First Affiliated Hospital of Zhengzhou University from August 2019 to August 2020 were analyzed retrospectively.Baseline data were collected and follow-up was performed.The thickness of local EAT was measured based on CMR image data.According to the follow-up results,they were divided into recurrence group and non-recurrence group.The differences between the two groups were compared.Results There was no statistical difference in the total operation time and total radiofrequency ablation time between the two groups(P>0.05).The EAT thickness of the right atrioventricular groove,anterior interventricular groove and right ventricular free wall in recurrence group was higher than those of non-recurrence group(P<0.05).Logistic regression analysis showed that the increased thickness of the right atrioventricular groove EAT was an independent risk factor for recurrence after radiofrequency ablation of idiopathic RVOT-PVCs.The OR(95%CI)was 1.618(1.055-2.483).The receiver operating characteristic(ROC)curve showed that the best cut-off value for predicting the recurrence of idiopathic RVOT-PVCs after radiofrequency ablation was the EAT thickness of the right atrioventricular groove 16.45 mm(P=0.003)and the area under the ROC curve(95%CI)was 0.800(0.678-0.922).Conclusion The thickness of EAT increases the risk of recurrence in patients with idiopathic RVOT-PVCs after radiofrequency ablation,which is an independent risk factor.

关 键 词：心外膜脂肪组织厚度 心脏磁共振 特发性右室流出道室性期前收缩 射频消融 

分 类 号：R541.73[医药卫生—心血管疾病]