全身PET/CT临床研究的现况与展望  

Total-body PET/CT current research and future perspectives

作　　者：蔡丹杰 石洪成 Cai Danjie;Shi Hongcheng(Department of Nuclear Medicine,Zhongshan Hospital,Fudan University Nuclear Medicine Institute of Fudan University Shanghai Institution of Medical Imaging,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院核医学科、复旦大学核医学研究所、上海市影像医学研究所,上海200032

出　　处：《中华核医学与分子影像杂志》2022年第1期41-43,共3页Chinese Journal of Nuclear Medicine and Molecular Imaging

基　　金：上海市临床重点专科项目 (shslczdzk03401)。

摘　　要：全身PET/CT较常规PET/CT的优势体现在:长轴向视野使得其系统灵敏度提高约40倍, 得以实现快速显像、低剂量显像以及全身动态显像。全身PET/CT或可以提高单位时间内检查患者的数量, 降低患者所受辐射剂量, 以及实时且动态地观察药物体内代谢过程。其高灵敏度也使长时间的延迟显像成为可能。除此之外, 其在新药研发以及药代动力学的研究等方面具有潜在优势。Comparing to the conventional PET/CT,the advantage of total-body PET/CT lies in the long axial field-of-view(LAFOV)which improves the system sensitivity by 40 times,allowing rapid scan,low-dosing imaging and total-body dynamic imaging.Total-body PET/CT can increase the throughput of patients,reduce the radiation dose,and observe the drug metabolism in vivo both real-time and dynamically.Its high sensitivity makes long-time delay scan possible in clinic research.Besides,it also has potential advantages in drugs development and in the field of pharmacokinetic researches.

关 键 词：全身成像 正电子发射断层显像术 体层摄影术 X线计算机 发展趋势 

分 类 号：R817.4[医药卫生—影像医学与核医学]