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作 者:阎腾龙 杨思雯 王煜倩 朱晓俊 周兴藩 马文军[4] 唐仕川 李珏 李涛[5] YAN Tenglong;YANG Siwen;WANG Yuqian;ZHU Xiaojun;ZHOU Xingfan;MA Wenjun;TANG Shichuan;LI Jue;LI Tao(Beijing Institute of Occupational Disease Prevention and Treatment,Beijing 100093,China;National Center for Occupational Safety and Health,National Health Commission of the People's Republic of China,Beijing 102308,China;Institute of Urban Safety and Environmental Science,Beijing Academy of Science and Technology,Beijing 100054,China;School of Public Health,Peking University,Beijing 100191,China;National Institute of Occupational Health and Poison Control,Chinese Center for Disease Control and Prevention,Beijing 100050,China)
机构地区:[1]北京市职业病防治研究院,北京100093 [2]国家卫生健康委职业安全卫生研究中心,北京102308 [3]北京市科学技术研究院城市安全与环境科学研究所,北京100054 [4]北京大学公共卫生学院,北京100191 [5]中国疾病预防控制中心职业卫生与中毒控制所,北京100050
出 处:《环境与职业医学》2021年第12期1307-1311,共5页Journal of Environmental and Occupational Medicine
基 金:北京市职业病防治研究院院长基金重大先导项目(ZFY2001001);北京市科研院改革发展项目(BJAST-RD-BMILP202108)。
摘 要:[背景]日光温室作为一种新型蔬菜生产方式已在全国范围内得到广泛应用,日光温室作业对血脂的影响值得关注。[目的]探讨日光温室作业与血脂异常的关系及家庭聚集性。[方法]选取我国西北某地区日光温室作业人员744人为温室组,以该地区231名大田作业农民为非温室组。检测两组人员血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDLC)和低密度脂蛋白胆固醇(LDLC)浓度。依据2007年临床血脂异常二分类标准判定血脂异常与否,采用多因素logistic回归模型和多水平多元线性回归模型探究血脂改变与日光温室作业的关系及家庭聚集性。[结果]温室组和非温室组血脂异常人数(构成比)分别为142(19.1%)和43(18.6%),差异无统计学意义(P> 0.05)。多因素logistic回归分析结果显示,年龄增大(OR=1.019,95%CI:1.001~1.038)和BMI升高(OR=1.162,95%CI:1.106~1.220)与血脂异常风险升高有关(均P <0.05),从事日光温室作业对血脂异常的影响无统计学意义(P> 0.05)。多水平多元线性回归分析显示,TC、HDLC和TG/HDLC改变有家庭聚集性(b=0.238,95%CI:0.132~0.430;b=0.044,95%CI:0.033~0.065;b=1.003,95%CI:0.947~1.059)(均P <0.05)。[结论]日光温室作业未明显增加血脂异常的发生率,但TC、HDLC和TG/HDLC指标水平在日光温室作业人员中存在家庭聚集性。[Background] As a new type of vegetable production method, solar greenhouse has been widely promoted nationwide. The influence of solar greenhouse working on blood lipid cannot be ignored.[Objective] The aim of the study is to explore the relationship between solar greenhouse working and blood lipid and family clustering.[Methods] A total of 744 solar greenhouse workers in northwestern China were selected as the greenhouse group, and 231 general open field farmers in the same area were selected as the non-greenhouse group. The levels of serum total cholesterol(TC), triglycerides(TG), high-density lipoprotein cholesterol(HDLC), and low-density lipoprotein cholesterol(LDLC) in the two groups were detected. Dyslipidemia was determined by a two-classification criteria in the national guideline of 2007. Multiple logistic regression model and multilevel multiple linear regression model were used to explore the relationship of blood lipid with solar greenhouse working, and its family clustering.[Results] The number of dyslipidemia cases in the greenhouse group and non-greenhouse group was 142(19.1%) and 43(18.6%),respectively, and the difference was not statistically significant(P > 0.05). The results of multiple logistic regression analysis showed that increasing age(OR=1.019, 95% CI: 1.001-1.038) and increased BMI(OR=1.162, 95% CI: 1.106-1.220) were related to elevated risk of dyslipidemia(all Ps < 0.05). The results of multilevel multiple linear regression model showed that the changes of TC, HDLC, and TG/HDLC had family clustering(b=0.238, 95% CI: 0.132-0.430;b=0.044, 95% CI: 0.033-0.065;b=1.003, 95% CI: 0.947-1.059)(all Ps < 0.05).[Conclusion] Solar greenhouse working does not significantly increase the incidence of dyslipidemia, but the levels of TC, HDLC, and TG/HDLC levels in the solar greenhouse workers have family clusters.
分 类 号:A139.2[哲学宗教—马克思主义哲学]
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