植物合成生物学领域发展态势的文献计量分析  

Analysis of the Development Trend in the Field of Plant Synthetic Biology

作　　者：郭晓真 张学福[1] GUO Xiao-zhen;ZHANG Xue-fu(Agricultural Information Institute of CAAS,Beijing 100081)

机构地区：[1]中国农业科学院农业信息研究所,北京100081

出　　处：《生物技术通报》2022年第2期289-296,共8页Biotechnology Bulletin

摘　　要：合成生物学作为一种颠覆性技术可应用于农业领域的创新发展,解决当前农业学科中的瓶颈问题。利用文献计量学方法从领域发表论文的时序数量分布、主题分布等探测当前合成生物学的基本态势。基于领域的主题分布可知,其中植物合成生物学这一主题是稳定存在的且主题规模处于稳定增长趋势。聚焦植物合成生物学这一主题方向,在构建引文网络的基础上利用主路径分析方法从知识流动角度探测植物合成生物学领域重要知识节点,内容涵盖介子油苷生物合成途径,重要催化酶功能解析、转录因子的调控作用,组学方法的应用,利用微生物酵母进行生物物质合成,这些内容表征了合成生物的核心理论技术。Synthetic biology,as a disruptive technology,can be applied to solve the bottleneck problem in current agricultural disciplines.In this study,bibliometrics is used to analyze the basic situation of synthetic biology from the time series,number distribution and topic distribution of published papers in the field.Based on the topic distribution in the field,it can be seen that the topic of plant synthetic biology is steadily increasing.Focusing on the topic of plant synthetic biology,the main path analysis was used to explore the important knowledge nodes in the development process of plant synthetic biology from the perspective of knowledge flow.Based on the main path analysis method the representative content glucosinolate as the representative secondary metabolite,including the mesotrioside biosynthetic pathway,the functional analysis of important catalytic enzymes,the regulation of transcription factors,the application of omics method,and the use of microbial yeast for biomass synthesis,which respectively characterized the core theory and technology of synthetic biology.

关 键 词：合成生物学 植物合成生物学 文献计量 发展态势分析 

分 类 号：G353.1[文化科学—情报学] Q81[生物学—生物工程]