基于灭菌效果监测的真空压力蒸汽灭菌器最优参数选取方法  

Optimal parameters selection of vacuum pressure steam sterilizer based on sterilization effect monitoring

作　　者：郭玉婷[1] 陈星月 张雪林[1] 罗洁妤 Guo Yuting;Chen Xingyue;Zhang Xuelin;Luo Jieyu(Sichuan Provincial Orthopedics Hospital,Chengdou Si chuan,610041)

机构地区：[1]四川省骨科医院,四川成都610041

出　　处：《现代科学仪器》2022年第1期215-220,共6页Modern Scientific Instruments

摘　　要：为提升真空压力蒸汽灭菌器灭菌效果,提出基于灭菌效果监测的真空压力蒸汽灭菌器最优参数选取方法。该方法使用温度压力测定仪、敷料型PCD灭菌包、恒温培养箱等设备,利用不同循环方式通过调整压力变化速率在合格条件与不合格条件下,从不同脉动深度、真空速率、密封时间、脉动正压值和脉动真空值等方面检测空压力蒸汽灭菌器灭菌效果,从检测结果中选取真空压力蒸汽灭菌器最优参数。实验结果表明:真空压力蒸汽灭菌器温度、时间参数分别为130℃、2.8min条件下,抽空深度分别为5kpa、20kpa时,最优脉冲次数分别为5次、10次;密封时间为400min时,脉动正压值和脉动真空值最优参数为-0.095mpa和0.09mpa,此时灭菌合格率达到100%;循环方式分别为低大气压、高大气压时,空气注入量最优参数分别为300 mL和400 mL。In order to improve the sterilization effect of vacuum pressure steam sterilizer,an optimal parameter selection method of vacuum pressure steam sterilizer based on sterilization effect monitoring was proposed.In this method,temperature and pressure measuring instrument,dressing PCD sterilization package,constant temperature incubator and other equipment were used to test the sterilization effect of air pressure steam sterilizer from the aspects of different pulse depth,vacuum rate,sealing time,pulse positive pressure value and pulse vacuum value under the qualified and unqualified conditions by adjusting the pressure change rate in different circulation modes The optimal parameters of vacuum pressure steam sterilizer.The results showed that:under the conditions of 130℃and 2.8 min of vacuum pressure steam sterilizer temperature and time,when the evacuation depth was 5 kPa and 20 kPa,the optimal pulse times were 5 times and 10 times respectively;when the sealing time was 400 min,the optimal parameters of pulsating positive presasure and pulsating vacuum value were-0.095 MPa and 0.09 MPa,and the sterilization qualified rate reached 100%;the circulation mode was low atmosphere The optimal parameters of air injection volume are 300mL and 400mL at high and high pressure,respectively.

关 键 词：灭菌效果 真空 蒸汽灭菌器 参数 脉动深度 真空速率 

分 类 号：TH771[机械工程—仪器科学与技术]