动态动脉硬化指数联合颈动脉超声与冠心病关系的研究  

Relationship between ambulatory arterial stiffness index combined with carotid ultrasound and coronary heart disease

作　　者：张俊雅 曾燕荣[1] 周静[1] 李春蕾[2] 刘冉[2] 马雪原 Zhang Junya;Zeng Yanrong;Zhou Jing;Li Chunlei;Liu Ran;Ma Xueyuan(Department of Ultrasound,Beijing Luhe Hospital,Capital Medical University,Beijing 101149,China.)

机构地区：[1]首都医科大学附属北京潞河医院超声科,北京101149 [2]首都医科大学附属北京潞河医院心内科,北京101149

出　　处：《中国循证心血管医学杂志》2022年第1期105-107,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的分析动态动脉硬化指数(AASI)联合颈动脉超声与冠状动脉粥样硬化性心脏病(冠心病)的关系。方法将2019年1月至2020年1月于北京潞河医院经冠状动脉(冠脉)造影确诊的216例冠心病患者作为研究对象,冠脉造影检查血管为单支病变者纳入对照组,多支病变纳入观察组,两组各108例。对比两组患者的血压、AASI、颈动脉狭窄、颈动脉内中膜厚度(IMT)、斑块积分及冠脉评分。结果两组患者的收缩压及舒张压对比无明显差异(P>0.05),均在正常血压范围内;AASI存在明显差异(P<0.05),观察组显著高于对照组;两组患者颈动脉狭窄中度狭窄对比无明显差异(P>0.05),观察组轻度狭窄明显低于对照组,但重度狭窄及闭塞明显高于对照组(P<0.05);两组患者的IMT、斑块积分及冠脉评分对比存在明显差异(P<0.05),且观察组明显高于对照组。结论AASI联合颈动脉超声检查可为冠心病的动脉硬化及斑块病变程度的评估提供临床参考,多支病变AASI高于单支病变,数值更接近1,多支病变的IMT、斑块积分及冠脉评分均高于单支病变,且多支病变的颈动脉狭窄程度更重。Objective To analyze the relationship between ambulatory arterial stiffness index(AASI)combined with carotid ultrasound and coronary heart disease(CHD).Methods CHD patients(n=216)diagnosed by coronary angiography were chosen from Beijing Luhe Hospital from Jan.2019 to Jan.2020.The patients with single-vessel lesion were selected into control group and those with multi-vessel lesion were selected into observation group(each n=108).The indexes of blood pressure,carotid artery stenosis,carotid artery intima-media thickness(CA-IMT),plaque integrals and coronary artery scores were compared between 2 groups.Results The comparison in systolic blood pressure(SBP)and diastolic blood pressure(DBP)had no significant difference(P>0.05)within the range of normal blood pressure,and comparison in AASI had significant difference(P<0.05)between 2 groups.The comparison in moderate stenosis of carotid artery had no significant difference(P>0.05)between 2 groups.The percentage of mild stenosis of carotid artery was significantly lower but percentage of severe stenosis and occlusion of carotid artery was significantly higher in observation group than that in control group(P<0.05).The comparisons in CA-IMT,plaque integrals and coronary artery scores had significant difference between 2 groups(P<0.05),and all of them were higher in observation group than those in control group.Conclusion AASI combined with carotid ultrasound can provide clinical diagnosis reference for reviewing the severity of atherosclerosis and plaque lesions of CHD.AASI in multi-vessel lesion is higher than that in single-vessel lesion,and the value is closer to 1.IMT,plaque integrals and coronary artery scores of multi-vessel lesion are higher than those of single-vessel lesion,and severity of carotid artery stenosis of multi-vessel lesion is higher.

关 键 词：冠心病 颈动脉超声 动态动脉硬化指数 

分 类 号：R541.4[医药卫生—心血管疾病]