针灸联合丁苯酞治疗大面积脑梗死术后早期疗效研究  

Clinical effect of acupuncture with butylphthalide on early intervention after large-scale cerebral infarction

作　　者：王玥[1] 黄雷[1] 张婷[1] WANG Yue;HUANG Lei;ZHANG Ting(The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410007,China)

机构地区：[1]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《陕西中医》2022年第3期367-370,共4页Shaanxi Journal of Traditional Chinese Medicine

基　　金：湖南省自然科学基金资助项目(2020JJ8066)。

摘　　要：目的:探讨针灸联合丁苯酞软胶囊对大面积脑梗死术后早期干预的临床疗效。方法:将98例大面积脑梗死术后患者分为观察组和对照组,每组49例,对照组采用常规治疗,观察组在对照组基础上给予针灸联合丁苯酞软胶囊治疗。比较两组临床疗效、神经功能、生活质量及颅内血流动力学。结果:观察组治疗总有效率为87.76%,高于对照组的71.43%(P<0.05)。治疗后,两组患者美国国立卫生研究院卒中量表(NIHSS)评分较治疗前下降(P<0.05),Barthel指数评分(BI)、SF-36生活质量量表评分较治疗前升高(均P<0.05),且观察组各项评分改善程度优于对照组(均P<0.05)。治疗后,两组患者大脑前动脉(ACA)、中动脉(MCA)平均血流速度均较治疗前升高,且观察组ACA、MCA平均血流速度高于对照组(均P<0.05)。结论:针灸联合丁苯酞软胶囊对大面积脑梗死术后患者进行早期干预疗效较好,有助于改善患者脑血流动力学和神经功能损伤,提高日常生活能力及生活质量。Objective:To investigate the clinical effect of acupuncture with butylphthalide on early intervention after large-scale cerebral infarction.Methods:98 cases of patients with large-scale cerebral infarction after operation were divided into observation group and control group,49 cases in each group.The control group received conventional treatment,and the observation group was given acupuncture with butylphthalide treatment on the basis of the control group.The clinical effect,neurological function,quality of life and intracranial hemodynamics were compared between the two groups.Results:The total effective rate of the observation group was 87.76%,significantly higher than 71.43%of the control group(all P<0.05).After treatment,NIHSS scores in the two groups were decreased compared with before treatment(all P<0.05),while BI and SF-36 scores were increased compared with before treatment(all P<0.05).The improvement of scores in the observation group was better than that in the control group(all P<0.05).After treatment,the mean flow velocity of ACA and MCA in the two groups were increased compared with before treatment,and the mean flow velocity of ACA and MCA in the observation group were higher than those in the control group(all P<0.05).Conclusion:The early intervention of acupuncture with butylphthalide and moxibustion in patients with large-scale of cerebral infarction was effective,which was helpful to improve the state of cerebral hemodynamics and neurological damage,improve the ability of daily life and quality of life.

关 键 词：脑梗死 针灸 丁苯酞软胶囊 早期干预 血流动力学 

分 类 号：R255.2[医药卫生—中医内科学]