黄葵胶囊联合泼尼松治疗儿童紫癜性肾炎32例  

Clinical Observation on Huangkui Capsules and Prednisone in Treating 32 cases of Henoch-Schonlein Purpura Nephritis in Children

作　　者：万单华 高向莹 李天 陶仲宾[2] 陈虹[2] WAN Danhua;GAO Xiangying;LI Tian;TAO Zhongbin;CHEN Hong(The First Clinical Medical College,Lanzhou University,Lanzhou 730000,China;The First Hospital,Lanzhou University)

机构地区：[1]兰州大学第一临床医学院,甘肃兰州730000 [2]兰州大学第一医院

出　　处：《西部中医药》2022年第2期96-98,共3页Western Journal of Traditional Chinese Medicine

基　　金：甘肃省科技厅自然科学基金(20JR5RA358)。

摘　　要：目的:探讨黄葵胶囊联合泼尼松治疗儿童过敏性紫癜性肾炎的临床疗效。方法:将65例符合纳入标准的紫癜性肾炎患儿,分为观察组32例与对照组33例,两组均用泼尼松等西药常规治疗,观察组口服黄葵胶囊,疗程为8周,观察两组治疗前后24小时尿蛋白、尿红细胞计数、β_(2)微球蛋白、血肌酐、尿素氮、总胆固醇及甘油三酯指标的变化情况。结果:治疗8周后,观察组24小时尿蛋白、尿红细胞计数、β_(2)微球蛋白、血清肌酐及血甘油三酯均较对照组下降,差异有统计学意义(P<0.05)。结论:黄葵胶囊联合西药常规治疗儿童紫癜性肾炎的疗效显著。Objective:To explore the clinical efficacy of Huangkui capsule combined with prednisone in the treatment of children with Henoch-schonlein purpura nephritis(HSPN).Methods:A total of 65 children who met the inclusion criteria were allocated to 32 cases of the observation group and 33 cases of the control group according to random number table method,both groups accepted conventional therapy of Western medicine,and the observation group took Huangkui capsule orally,and the course was eight weeks,to observe the changes of 24-hour urinary protein,urine red blood cell count,β_(2) microglobulin,serum creatinine,urea nitrogen,total cholesterol and triglyceride before and after treating in both groups.Results:After eight weeks of treatment,24-hour urinary protein,urine red blood cell count,β_(2) microglobulin,serum creatinine and triglyceride of the observation group lowered compared with these of the control group,and the difference had statistical meaning(P<0.05).Conclusion:Huangkui capsule combined with prednisone in the treatment of HSPN in children could obtain notable effects,

关 键 词：紫癜性肾炎 黄葵胶囊 激素 儿童 

分 类 号：R692.34[医药卫生—泌尿科学]