骨水泥植入综合征的研究进展及预防  

Research Progress and Prevention of Bone Cement Implantation Syndrome

作　　者：董强[1] 王琪[2] 晁博 王琦[2] 韩超[1] DONG Qiang;WANG Qi;CHAO Bo;WANG Qi;HAN Chao(Hip Joint Ward,Tianjin Hospital,Tianjin,Tianjin 300211;Tianjin Adverse Drug Reaction Monitoring Center,Tianjin 300191;LinkDoc Technology Co.,Ltd.,Beijing 100080)

机构地区：[1]天津市天津医院髋关节病区,天津300211 [2]天津市药品不良反应监测中心,天津300191 [3]零氪信息技术(北京)有限公司,北京100080

出　　处：《中国医疗器械信息》2022年第3期45-48,共4页China Medical Device Information

摘　　要：骨水泥植入综合征(BCIS)是指在手术中置入骨水泥时患者可能出现的一系列严重临床并发症,以顽固性低氧血症、血压骤降以及伴或不伴意识障碍为主要临床表现。BCIS多在骨水泥置入前后的时段发生,当前的主要治疗方法为及时使用血管活性药物、迅速补充血容量、足量的液体支持以及呼吸循环支持等。正确认识BCIS患者的各种危险因素,了解骨水泥的各种特性,明晰不良综合征报告等级,选择合适的麻醉方式是预防BCIS的重要前提。术中要注意细致轻柔操作,降低在打入假体过程中的髓腔压力,减少栓塞风险。此外,围手术期使用激素等药物也可以有效降低BCIS的风险。Bone cement implantation syndrome(BCIS)is a potentially fatal clinical syndrome that occurs during bone cement implantation surgery,which is mainly manifested as sudden hypotension,hypoxemia,or loss of consciousness.BCIS mostly occurs at the time or implantation of bone cement or prosthesis.At present,the main treatment methods include rapid blood volume supplementation,circulatory function support using vasoactive drugs,oxygen therapy,and respiratory function support through non-invasive mechanical ventilation.Identify high-risk patients with BCIS,clarify the report level of syndrome,choose appropriate anesthesia methods and close monitoring are the prerequisites for preventing BCIS.Reducing the embolus load and reducing the pressure of the medullary cavity during the implantation of the prosthesis can greatly reduce the probability of disease.In addition,perioperative use of drugs such as hormones can also effectively reduce the risk of BCIS.

关 键 词：骨水泥 植入综合征 不良事件 

分 类 号：TH781[机械工程—仪器科学与技术]