2016—2019年浙江省手足口病流行特征  

Epidemiological characteristics of hand, foot and mouth disease in Zhejiang Province from 2016 to 2019

作　　者：庞孟涛[1] 李傅冬[2] 林君芬[2] 古雪 PANG Mengtao;LI Fudong;LIN Junfen;GU Xue(Department of Personnel,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China;Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)

机构地区：[1]浙江省疾病预防控制中心人事教育处,浙江杭州310051 [2]浙江省疾病预防控制中心,浙江杭州310051

出　　处：《预防医学》2022年第3期307-310,共4页CHINA PREVENTIVE MEDICINE JOURNAL

摘　　要：目的了解2016—2019年浙江省手足口病流行特征,为预防手足口病提供依据。方法通过国家疾病监测信息报告管理系统收集2016—2019年浙江省手足口病病例资料,采用描述性流行病学方法分析2016—2019年浙江省手足口病的时间分布、人群分布、地区分布和病原分型变化。结果 2016—2019年浙江省共报告手足口病642 305例,各年发病率分别为335.88/10万、147.76/10万、435.63/10万和221.77/10万,呈隔年升高趋势。其中重症病例121例,死亡病例9例。发病具有季节性,每年5—7月为发病高峰。年均发病率前三位的地区依次为宁波市、金华市和温州市;舟山市年均发病率最低。1~5岁儿童537 738例,占83.72%;散居儿童419 408例,占65.30%。男性年均发病率为328.23/10万,高于女性的239.99/10万(P<0.05)。优势病原逐渐由肠道病毒71型转变为柯萨奇病毒A组16型;其他肠道病毒仍为主要病原。结论 2016—2019年浙江省手足口病呈隔年升高、夏秋季高发特征;散居儿童易感;柯萨奇病毒A组16型逐渐成为优势病原。ObjectiveTo investigate the epidemiological characteristics of hand, foot and mouth disease( HFMD) in Zhejiang Province, so as to provide insights into HFMD control.MethodsThe incidence of HFMD in Zhejiang Province from 2016 to 2019 was collected from National Notifiable Disease Reporting System. The temporal distribution, human distribution, regional distribution and pathogenic typing of HFMD were descriptively analyzed in Zhejiang Province from2016 to 2019.ResultsTotally 642 305 cases with HFMD were reported in Zhejiang Province from 2016 to 2019, including 121 severe cases and 9 fatal cases. The annual incidence of HFMD was 335.88/10;, 147.76/10;, 435.63/10;and221.77/10;, respectively. The incidence of HFMD peaked from May to July each year, and the three highest annual incidence included Ningbo, Jinhua and Wenzhou cities, while the lowest annual incidence was seen in Zhoushan City. The HFMD cases were predominantly found in children at ages of 1 to 5 years( 537 738 cases, 83.72%), and in children living at home( 419 408 cases, 65.30%). The average annual incidence of HFMD was higher in males than in females( 328.23/10;vs. 239.99/10;P<0.05). The dominant pathogens gradually shifted from enterovirus 71( EV71) to Coxsachievirus A16( CA16), and other enteroviruses remained as the main pathogenic subtypes.ConclusionsThe incidence HFMD was high in summer and autumn in Zhejiang Province from 2016 to 2019. Children living at home are at a high risk of HFMD, and CA16 type gradually became the dominant pathogen of HFMD.

关 键 词：手足口病 流行病学特征 肠道病毒71型 柯萨奇病毒A组16型 

分 类 号：R725.1[医药卫生—儿科]