输卵管通液术联合中药治疗输卵管炎性不孕症的临床疗效观察  

Objective to Observe the Clinical Effect of Salpingostomy Combined with Traditional Chinese Medicine in the Treatment of Salpingitis Infertility

作　　者：王海明 张春晓 张丽欣 WANG Hai-ming;ZHANG Chun-xiao;ZHANG Li-xin(Reproductive center of Affiliated Hospital of Chifeng University,Chifeng Inner Mongolia 024000)

机构地区：[1]赤峰学院附属医院生殖中心,内蒙古赤峰024000

出　　处：《世界中西医结合杂志》2022年第1期188-191,共4页World Journal of Integrated Traditional and Western Medicine

基　　金：内蒙古自治区高等学校科学研究项目(81201844)。

摘　　要：目的观察输卵管通液术联合中药治疗气滞血瘀证输卵管炎性不孕症的临床疗效。方法选取2018年1月—2019年12月期间赤峰学院附属医院生殖中心收治的气滞血瘀证输卵管炎性不孕症患者100例,按照随机数字表法分为对照组和治疗组,每组各50例。对照组给予输卵管通液术治疗,治疗组在对照组治疗基础上给予少腹逐瘀汤治疗。观察两组患者临床治疗效果,输卵管通畅程度,血清炎性因子水平[C反应白蛋白(C-reactive protein,CRP)、白细胞介素-6(Interleukin 6,IL-6)及肿瘤坏死因子-α(Tumor necrosis factor,TNF-α)],妊娠率及焦虑、抑郁情况。结果治疗后治疗组总有效率为88.0%(46/50)高于对照组64.0%(32/50),差异有统计学意义(P<0.05)。治疗后治疗组患者输卵管通畅总有效率90.0%(45/50)明显高于对照组66.0%(33/50),差异有统计学意义(P<0.05)。两组患者治疗后CRP、TNF-α、IL-6含量均较治疗前降低,差异有统计学意义(P<0.05);且治疗组血清CRP、TNF-α、IL-6水平较对照组明显降低,差异有统计学意义(P<0.05)。治疗后治疗组成功妊娠54.0%(27/50)明显高于对照组26.0%(13/50),差异有统计学意义(P<0.05)两组患者治疗后SAS、SDS评分均较治疗前明显降低,差异有统计学意义(P<0.05);且治疗组SAS、SDS评分均较对照组明显降低,差异有统计学意义(P<0.05)。结论输卵管通液术联合中药治疗气滞血瘀证输卵管炎性不孕症患者临床效果显著,可有效改善输卵管通畅程度,降低炎性反应,提高妊娠率,值得临床推广。Objective to observe the clinical effect of salpingostomy combined with traditional Chinese medicine in the treatment of tubal inflammatory infertility of Qi stagnation and blood stasis syndrome.Methods A total of 100 patients with tubal inflammatory infertility with Qi stagnation and blood stasis syndrome in our hospital were selected and divided into a control group and a treatment group according to a random number table,with 50 cases in each group.The control group was treated with tubal drainage,and the treatment group was treated with Shaofu Zhuyu Decoction on the basis of the control group.The clinical treatment effect of the two groups of patients,the degree of oviduct patency,the level of related factors in the serum,pregnancy rate and safety analysis were observed in the two groups of patients.Results After treatment,the total effective rate of the treatment group was 88.0%(46/50),which was higher than that of the control group,64.0%(32/50),and the difference was statistically significant(P<0.05).After treatment,the total effective rate of tubal patency in the treatment group was 90.0%(45/50),which was significantly higher than that in the control group,66.0%(33/50),with a statistically significant difference(P<0.05).After treatment,the levels of CRP,TNF-αand IL-6 in the two groups were lower than those before treatment,and the difference was statistically significant(P<0.05).decreased,and the difference was statistically significant(P<0.05).After treatment,54.0%(27/50)of successful pregnancy in the treatment group was significantly higher than 26.0%(13/50)in the control group,with a statistically significant difference(P<0.05).The SAS and SDS scores of the two groups after treatment were significantly higher than those before treatment.The difference was statistically significant(P<0.05);and the SAS and SDS scores in the treatment group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The combination of salpingostomy and tradi

关 键 词：输卵管炎 输卵管通液术 不孕症 中药 

分 类 号：R271.14[医药卫生—中医妇科学]