基于氧化锌/碳纳米纤维材料的氧氟沙星电化学传感器的构建及应用  

Construction and application of electrochemical sensor for ofloxacin detection based on zinc oxide/carbon nanofiber

作　　者：王朝琳 魏友利[1] 李薇 韩梅 司晓晶 WANG Chaolin;WEI Youli;LI Wei;HAN Mei;SI Xiaojing(School of Public Health and Nursing,Shanghai Aurora College,Shanghai 201908;Department of Food Science,Shanghai Business School,Shanghai 200235)

机构地区：[1]上海震旦职业学院公共卫生与护理学院,上海201908 [2]上海商学院食品系,上海200235

出　　处：《分析试验室》2022年第2期171-174,共4页Chinese Journal of Analysis Laboratory

基　　金：上海市自然科学基金(20ZR1440200);上海市晨光计划(C20190012)项目资助;。

摘　　要：通过静电纺丝技术合成碳纳米纤维,以循环伏安法在此碳纤维上电聚合乙酸锌制备复合纳米材料作为一种新型的电化学增敏剂,用于修饰玻碳电极,开发了一种基于碳纤维和氧化锌复合材料的新型电化学传感器(ZnO/CNF/GCE)。使用循环伏安法、差分脉冲伏安法等进行电化学催化性能的研究,并优化实验条件。结果表明,与裸电极相比,在pH 5.5磷酸盐缓冲溶液中,ZnO/CNF/GCE修饰电极能使氧氟沙星的峰电流明显提升,线性范围1~200μmol/L,检测限为0.33μmol/L。该ZnO/CNF/GCE修饰电极已用于氧氟沙星滴耳液中氧氟沙星的含量测定。In this experiment,carbon nanofibers were synthesized by electrospinning technology,and cyclic voltammetry was used to electropolymerize zinc acetate on the carbon fibers to prepare composite nanomaterials as a new type of electrochemical sensitizer for modifying glassy carbon electrodes.A new type of electrochemical sensor(ZnO/CNF/GCE)was constructed based on carbon fiber and zinc oxide composite nanomaterials.Cyclic voltammetry(CV)and differential pulse voltammetry(DPV)were used to study the electrochemical catalytic performance and optimize the experimental conditions of the electrochemical sensor.Compared with the GCE,the results showed that the ZnO/CNF/GCE modified electrode could significantly increase the peak current of ofloxacin in the phosphate buffered solution with pH 5.5.The linear range was 1 to 200μmol/L and the detection limit was about 0.33μmol/L.The ZnO/CNF/GCE modified electrode can be used to determine the content of ofloxacin in ofloxacinear drops。

关 键 词：氧氟沙星 电化学传感器 碳纳米纤维 氧化锌 

分 类 号：O657.1[理学—分析化学] R917[理学—化学]