基于羟基化酞菁锌-石墨烯纳米材料的和厚朴酚电化学传感器的构建及其应用  

Construction and application of honokiol electrochemical sensor based on zinc hydroxyphthalocyanine functionalized graphene oxide nanocomposite

作　　者：陈志红[1] 张俊霞[1] 史艳梅[1] 苗明三[1] 李秀敏 CHEN Zhihong;ZHANG Junxia;SHI Yanmei;MIAO Mingsan;LI Xiumin(Academy of Chinese Medicine Sciences,Henan University of Chinese Medicine,Zhengzhou 450046;Department of Microbiology and Immunology,New York Medical College,New York 10595,USA)

机构地区：[1]河南中医药大学中医药科学院,郑州450046 [2]纽约医学院微生物和免疫学系,美国纽约10595

出　　处：《分析试验室》2022年第2期192-196,共5页Chinese Journal of Analysis Laboratory

基　　金：河南省科技攻关项目(212102311037);河南中医药大学(03301232,00104358)项目资助。

摘　　要：通过非共价作用制备了可溶性四羟基酞菁锌-石墨烯纳米复合材料,并将其应用于构建新型高灵敏度和厚朴酚电化学传感器。由于水溶性四羟基酞菁锌和石墨烯的协同作用,显著提高了纳米复合材料的比表面积和导电性,增强了和厚朴酚的电化学响应。在最优实验条件下测定,和厚朴酚在0.01~1.0μmol/L和1.0~100μmol/L范围内呈良好的线性关系,检出限为4.0 nmol/L。将该方法可应用于实际样品厚朴提取物中和厚朴酚含量的测定。A new zinc tetrahydroxyphthalocyanine(ZnPc-OH)-graphene oxide(rGO)nanocomposite was fabricated via non-covalent interaction,and it could be employed as an electrode material to construct a high sensitive electrochemical sensor for honokiol.The electrochemical response of honokiol was enhanced by the remarkably increased specific surface area and conductivity of the rGO-ZnPc-OH nanocomposite due to the synergistic effect of rGO and water-soluble ZnPc-OH.Under the optimized conditions,the rGO-ZnPc-OH electrochemical sensor of honokiol exhibited a good linear relationship in the ranges of 0.01-1.0μmol/L and 1.0-100μmol/L with a detection limit of 4 nmol/L.The method was applied to the determination of honokiol in the extract of Magnolia officinalis with satisfactory results.

关 键 词：和厚朴酚 羟基化酞菁锌 石墨烯 电化学传感器 

分 类 号：O657.1[理学—分析化学]