电针益肾填髓组穴治疗髓海不足型阿尔茨海默病的临床效果  

Clinical effect of the acupoints combination of kidney-benefiting and marrow-filling of electroacupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency

作　　者：刘勇[1] 虞颢珩 LIU Yong;YU Haoheng(The First Department of Acupuncture and Moxibustion,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin150040,China;Graduate School,Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin150040,China)

机构地区：[1]黑龙江中医药大学附属第一医院针灸一科,黑龙江哈尔滨150040 [2]黑龙江中医药大学研究生院,黑龙江哈尔滨150040

出　　处：《中国医药导报》2022年第4期136-139,共4页China Medical Herald

基　　金：黑龙江中医药大学研究生创新科研项目(2020yjscx026);黑龙江省中医药科研项目(ZHY2020-119)。

摘　　要：目的探讨电针益肾填髓组穴治疗髓海不足型阿尔茨海默病的临床效果。方法选取2019年9月至2020年11月黑龙江中医药大学附属第一医院针灸一科门诊及住院部所招募的60例阿尔茨海默病患者,根据随机数字表法分为针刺组(30例)和电针组穴组(30例)。针刺组给予传统针灸治疗,电针组穴组给予电针益肾填髓组穴治疗。两组均治疗4周。比较两组治疗前后简易精神状态检查表(MMSE)、中医痴呆证候分型量表(SDSD)、蒙特利尔认知评估(MoCA)的数值变化,并计算疗效指数作为疗效评估。结果治疗后两组MMSE、MoCA评分较治疗前升高,且电针组穴组高于针刺组(P<0.05);治疗后两组SDSD评分较治疗前降低,且电针组穴组低于针刺组(P<0.05)。治疗后电针组穴组MMSE、SDSD、MoCA疗效指数高于针刺组(P<0.05)。结论传统针灸与电针益肾填髓组穴均对髓海不足型阿尔兹海默病有确切疗效,且电针益肾填髓组穴治疗髓海不足型阿尔兹海默病效果优于传统针刺。Objective To explore the clinical effect of the acupoints combination of kidney-benefiting and marrow-filling of electroacupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency.Methods A total of 60 patients recruited from the outpatient and inpatient department of the First Affiliated Hospital of Heilongjiang University of Chinese medicine from September 2019 to November 2020 were selected,according to random number table method,they were divided into acupuncture group(30 cases)and electroacupuncture point group(30 cases).The acupuncture group was treated with traditional acupuncture and moxibustion,and the electroacupuncture point group was treated with acupoints combination of kidney-benefiting and marrow-filling.Both groups were treated for four weeks.The mini mental state examination(MMSE),classification of dementia syndrome in traditional Chinese medicine(SDSD),and Montreal cognitive assessment(MoCA)was compared between the two groups before and after treatment,and the efficacy index was calculated as the efficacy evaluation.Results After treatment,the MMSE and MOCA scores of the two groups were higher than those before treatment(P<0.05),and the electroacupuncture point group was higher than that of the acupuncture group(P<0.05);the SDSD scores of the two groups were lower than those before treatment(P<0.05),and the electroacupuncture point group was lower than that of the acupuncture group(P<0.05).The therapeutic indexes of MMSE,SDSD and MOCA in electroacupuncture point group were higher than those of the acupuncture group(P<0.05).Conclusion Both traditional acupuncture and acupoints combination of kidney-benefiting and marrow-filling have definite curative effects on Alzheimer’s disease with syndrome of marrow sea insufficiency,and acupoints combination of kidney-benefiting and marrow-filling is better than traditional acupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency.

关 键 词：阿尔兹海默病 益肾填髓 电针 穴位配伍 随机对照试验 

分 类 号：R246.6[医药卫生—针灸推拿学]