不同加工方法的“杀酶保苷”作用及对黄芩片质量的影响  

Influence of different processing methods on the effect of’glycoside protection by inactivating enzyme’and the quanlity of Scutellariae Radix pieces

作　　者：韩喜桃 唐雅楠 刘子琴 王宏月 包丽媛 李飞[1] 毛民 杜红[1] HAN Xi-tao;TANG Ya-nan;LIU Zi-qin;WANG Hong-yue;BAO Li-yuan;LI Fei;MAO Min;DU Hong(School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China;Beijing Tongrentang Science and Technology Co.,Ltd.,Pharmaceutical Factory,Beijing 100079,China)

机构地区：[1]北京中医药大学中药学院,北京102488 [2]北京同仁堂科技发展股份有限公司制药厂,北京100079

出　　处：《中华中医药杂志》2022年第1期120-124,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：北京市中药炮制技术传承基地建设项目。

摘　　要：目的:优选黄芩的产地加工方法,研究不同加工方法的"杀酶保苷"作用及对黄芩片质量的影响。方法:采用不同加工方法加工黄芩片,考察各黄芩片外观性状、色度、水分、酶灭活情况及黄芩苷的含量,综合评价各产地加工方法对黄芩片质量的影响及"杀酶保苷"效果。结果:先烘(100℃)后切、先蒸后切的饮片外观性状较好,黄芩苷含量较高,且能达到"杀酶保苷"的目的;先切后烘的饮片外观性状较差,饮片挂火色,黄芩苷含量较低,且无法保证"杀酶保苷"的效果。结论:黄芩产地加工方法以先烘(100℃)后切、先蒸后切为宜。Objective:To optimize the processing methods of Scutellariae Radix pieces,to study the influence of different processing methods on the effect of’glycoside protection by inactivating enzyme’and the quanlity of Scutellariae Radix pieces.Methods:The appearance characteristics,chroma,moisture,enzyme inactivation and baicalin content of each Scutellariae Radix pieces were investigated by processing of Scutellariae Radix pieces with different processing methods.The effects of different habitat processing methods on the quality of Scutellariae Radix pieces and the’glycoside protection by inactivating enzyme’effect were evaluated synthetically.Results:The characteristics of appearance baking(100℃)before cutting and steaming before cutting were better,the baicalin content was higher,and the purpose of’glycoside protection by inactivating enzyme’could be achieved.Scutellariae Radix pieces of cuting after baking had poor appearance characteristics,the decoction pieces had a fire color,the baicalin content was low,and’glycoside protection by inactivating enzyme’couldn’t be guaranteed.Conclusion:The processing technology adopted in the production area is baking(100℃)before cutting and steaming before cutting.

关 键 词：黄芩 产地加工 黄芩片 杀酶保苷 外观性状 黄芩苷 

分 类 号：R283.6[医药卫生—中药学]