特制新会陈皮饮片的炮制工艺研究  

Research on the processing technology of special-made Xinhui Tangerine peel decoction pieces

作　　者：余香 龚千锋[2] 梁志云 张俊杰 张健民 张明 YU Xiang;GONG Qian-feng;LIANG Zhi-yun;ZHANG Jun-jie;ZHANG Jian-min;ZHANG Ming(Xinhui Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,Jiangmen 529100,China;Jiangxi University of Chinese Medicine,Nanchang 330004,China)

机构地区：[1]广州中医药大学附属新会中医院,江门529100 [2]江西中医药大学,南昌330004

出　　处：《中华中医药杂志》2022年第1期368-371,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家中医药管理局中药标准化行动计划项目(No.ZYBZH-Y-IX-27)。

摘　　要：目的:优选特制新会陈皮饮片的炮制工艺。方法:采用正交试验法考察蛇胆汁量、饮片片型和烘干温度3个因素对特制新会陈皮饮片炮制工艺的影响,以橙皮苷、川陈皮素、橘皮素和稀乙醇浸出物含量及饮片性状为指标进行综合性评价,内在成分含量通过HPLC测定,流动相用乙腈和水梯度洗脱,进样量:10μL,流速:1.0 mL/min,柱温:30℃,橙皮苷、川陈皮素、橘皮素的检测波长分别为284、330、330 nm。结果:最佳炮制工艺为每10克陈皮用蛇胆汁量8 g,陈皮切丝,烘干温度为65℃,特制新会陈皮呈黑棕色,气腥香,味咸苦,橙皮苷、川陈皮素和橘皮素含量为2.416%、0.272%、0.185%,稀乙醇浸出物含量为45.17%。结论:优选的炮制工艺方法为特制新会陈皮饮片保质、保量提供了科学依据。Objective:To optimize the processing technology of special-made Xinhui Tangerine peel decoction pieces.Methods:Orthogonal test was used to investigate the effects of the amount of snake bile,the type of prepared slices and the drying temperature on the processing technology of prepared slices of the special-made Xinhui Tangerine peel decoction pieces.Comprehensive evaluation was carried out with the content of hesperidin,chuanxifen,hesperetin and dilute alcohol extracts and the properties of decoction pieces as indicators.The content of internal components was determined by HPLC.The mobile phase was eluted with a gradient of acetonitrile and water.Injection volume:10μL,flow rate:1.0 mL/min,column temperature:30°C,and the detection wavelengths of hesperidin,chuanxifen,and hesperetin was 284,330,330 nm,respectively.Results:The best processing technology was 8 g of snake bile per 10 g of Tangerine peel,sliced Tangerine peel,and drying temperature was 65℃.The special-made Xinhui Tangerine peel decoction pieces was black brown,with fragrant air and salty taste.The content of hesperidin,chuanxifen and hesperetin were 2.416%,0.272%,0.185%,respectively,and the dilute alcohol extract was 45.17%.Conclusion:The optimal processing method provided scientific basis for the quality and quantity of the prepared slices of special-made Xinhui Tangerine peel decoction pieces.

关 键 词：特制新会陈皮饮片 炮制工艺 HPLC 浸出物测定 综合性评价 

分 类 号：R283.6[医药卫生—中药学]