多指标联合监测对子痫前期不良围产儿预后的影响  

The effect of multi-indicator combined monitoring on the prognosis of poor perinatal infants with preeclampsia

作　　者：钟艳铃 李桂联 康娇仪 麦连弟 Zhong Yanling;Li Guilian;Kang Jiaoyi;Mai Liandi(Third Affiliated Hospital of Guangdong Medical University(Longjiang Hospital,Shunde District,Foshan City),Guangzhou Guangdong,528318,China)

机构地区：[1]广东医科大学附属第三医院(佛山市顺德区龙江医院),广东广州528318

出　　处：《中外女性健康研究》2022年第1期1-2,13,共3页Women＇s Health Research

摘　　要：目的探讨多指标联合监测在子痫前期不良围产儿预后中的应用价值。方法回顾性分析本院2018年1月至2020年10月收治子痫前期孕妇60例,根据临床表现的严重程度分为子痫前期者30例(子痫前期组)和重度子痫前期者30例(重度子痫前期组),同期选择30例正常孕妇(对照组)。所有研究对象均采用手动血压监测、无刺激胎心监护(NST)以及彩色多普勒超声测定脐动脉血流阻力。比较三组孕妇1d平均血压、NST情况、S/D比值以及围产儿不良预后情况。结果三组孕妇1d的平均收缩压、1d的平均舒张压及S/D比值均存在明显差异性(F=90.142,F=12.304,F=351.087,P<0.001);三组孕妇的无反应型NST、可疑反应型NST、反应型NST均存在统计学意义(χ^(2)=0.024,P=0.016;χ^(2)=0.029,P=0.026;χ^(2)=0.055,P<0.001);三组围产儿肺透明膜病发生率存在差异性(χ^(2)=2.109,P=0.039),三组新生儿死亡、新生儿缺血缺氧性脑病、新生儿窒息的发生率比较无统计学意义(P>0.05)。结论手动血压监测联合胎心监护、脐血流阻力S/D比值有助于更好地识别母婴发生不良结局的风险,针对不良围产儿预后存在一定的预测价值。Objective:To investigate the application value of multiple indicators combined monitoring in perinatal prognosis of preeclampsia.Methods:A retrospective analysis was performed on 60 pregnant women with preeclampsia admitted to our hospital from January 2018 to October 2020.According to the severity of clinical manifestations,they were divided into 30 cases of preeclampsia(preeclampsia group)and 30 cases of severe preeclampsia(severe preeclampsia group),and 30 cases of normal pregnant women(control group)were selected during the same period.All subjects underwent manual blood pressure monitoring,non-stimulating fetal heart monitoring(NST),and color Doppler ultrasound to measure the umbilical artery blood flow resistance.The mean blood pressure,NST,S/D ratio and perinatal adverse prognosis were compared among the three groups.Results:There were significant differences in mean systolic blood pressure,mean diastolic blood pressure and S/D ratio at 1d among the three groups(F=90.142,F=12.304,F=351.087,P<0.001).There were statistically significant differences in non-reactive NST,suspicious reactive NST and reactive NST among the three groups(χ^(2)=0.024,P=0.016;χ^(2)=0.029,P=0.026;χ^(2)=0.0055,P<0.001);There was significant difference in the incidence of hyaline membrane disease among the three groups(χ^(2)=2.109,P=0.039),but there was no significant difference in the incidence of neonatal death,neonatal hypoxic encephalopathy and neonatal asphyxia among the three groups(P>0.05).Conclusion:Manual blood pressure monitoring combined with fetal heart monitoring and umbilical cord blood flow resistance S/D ratio can better identify the risk of maternal and infant adverse outcomes,and has certain predictive value for the prognosis of adverse perinatal outcomes.

关 键 词：子痫前期 不良围产儿 预后 手动血压监测 胎心监护 脐血流阻力S/D 

分 类 号：R714.25[医药卫生—妇产科学]