阴道微生态与HPV感染的相关性研究  

Study on correlation between vaginal microecology and HPV infection

作　　者：吴瑛 张敏[1] 王苏立 张金玉 WU Ying;ZHANG Min;WANG Suli;ZHANG Jinyu(Women′s Hospital of Nanjing Medical University/Nanjing Maternity and Child Health Care Hospital,Nanjing,Jiangsu 210004,China)

机构地区：[1]南京医科大学附属妇产医院/南京市妇幼保健院,江苏南京210004

出　　处：《现代医药卫生》2022年第5期751-754,共4页Journal of Modern Medicine & Health

摘　　要：目的评估妇女人乳头瘤病毒(HPV)感染与需氧菌性阴道炎、细菌性阴道病(BV)、外阴阴道假丝酵母菌病及滴虫性阴道炎的关系。方法选取2019年1-12月在该院妇科就诊的进行随机宫颈筛查的妇女4139例作为研究对象,使用聚合酶链反应检测宫颈样本HPV DNA基因分型并对阴道微生态进行评估。结果HPV16感染与BV独立相关;HPV6、11、18感染与BV无关。结论BV是HPV16感染的高危因素。Objective To evaluate the relationship between human papillomavirus(HPV)infection in women and aerobic bacterial vaginitis,bacterial vaginosis(BV),vulvovaginal candidiasis,and trichomonas vaginitis.Methods A total of 4139 women who visited the department of gynecology of this hospital from January to December 2019 and underwent random cervical screening were selected.HPV DNA genotyping of cervical samples was performed using polymerase chain reaction and vaginal microecology was assessed.Results HPV16 infection was independently associated with BV.HPV6,11 and 18 were not significantly associated with BV.Conclusion BV is a high risk factor for HPV16 infection.

关 键 词：乳头状瘤病毒科 感染 阴道 需氧细菌 阴道炎 细菌性阴道病 外阴阴道念珠菌病 滴虫性阴道炎 

分 类 号：R711.31[医药卫生—妇产科学]