灌注栓塞术治疗原发性肝癌患者术后癌性疲乏及护理体会  

Nursing experience in patients with primary hepatic carcinoma treated by perfusion embolization and their postoperative cancer-related fatigue

作　　者：米伟 MI Wei(Department of Imaging,the Tianyou Hospital Affiliated to Wuhan University of Science and Technology,Hubei,Wuhan 430064,China)

机构地区：[1]武汉科技大学附属天佑医院影像科,湖北武汉430064

出　　处：《中国医药科学》2022年第4期100-104,129,共6页China Medicine And Pharmacy

摘　　要：目的观察肝动脉灌注栓塞术联合对应性护理干预原发性肝癌术后癌性疲乏患者的临床疗效。方法选择2019年7月至2020年7月于武汉科技大学附属天佑医院肿瘤科治疗的88例原发性肝癌术后癌性疲乏患者为本研究对象,按随机数字表法分为观察组和对照组,每组各44例,对照组给予肝动脉灌注栓塞术联合常规护理,观察组给予肝动脉灌注栓塞术联合对应性护理。治疗前、后检测两组患者血清甲胎蛋白(AFP)、癌胚抗原(CEA)、血管内皮生长因子(VEGF)水平及血清肝功能标志物:丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆红素(TBIL),比较两组患者Piper疲乏自评修正量表(RPFS)和生存质量表(QLQ-C30),评价两组患者的临床疗效及护理满意度。结果观察组AFP、CEA、VEGF水平低于对照组(P<0.05),观察组ALT、AST、TBIL水平低于对照组(P<0.05),观察组RPFS评分低于对照组(P<0.05),观察组QLQ-C30评分高于对照组(P<0.05),观察组护理总满意度为88.64%,对照组护理总满意度为70.45%,观察组护理总满意度高于对照组(P<0.05),观察组总有效率为86.36%,高于对照组的65.91%(P<0.05)。结论肝动脉灌注栓塞术联合对应性护理干预原发性肝癌术后癌性疲乏患者可以降低患者AFP、CEA、VEGF水平,恢复患者肝功能,改善患者术后癌性疲乏,提高患者生活质量,提升患者护理满意度及临床疗效。Objective To observe the clinical efficacy of hepatic artery perfusion embolization combined with targeted nursing intervention in patients with cancer-related fatigue after primary hepatic carcinoma surgery.Methods A total of 88 patients with cancer-related fatigue after primary hepatic carcinoma surgery treated in the oncology department of Tianyou Hospital Affiliated to Wuhan University of Science and Technology from July 2019 to July 2020 were selected as the subjects of the study.They were divided into the observation group and the control group by the random number table method,with 44 cases in each group.The control group was given hepatic artery perfusion embolization combined with routine nursing,while the observation group was given hepatic artery perfusion embolization combined with targeted nursing.The levels of s erum alpha fetoprotein(AF P),carcinoembryonic antigen(CEA),vas cular endothelial growth factor(VEGF)and serum markers of liver function including alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBIL)were measured before and after treatment.The Revised Piper Fatigue Scale(RPFS)and quality of life scale(QLQ-C30)scores were compared between the two groups.The clinical efficacy and nursing satisfaction of the two groups were evaluated.Results The levels of AFP,CEA and VEGF in the observation group were lower than those in the control group(P<0.05);the levels of ALT,AST and TBIL in the observation group were lower than those in the control group(P<0.05);the RPFS score in the observation group was lower than that in the control group(P<0.05);the QLQ-C30 score in the observation group was higher than that in the control group(P<0.05).The nursing satisfaction in the observation group(88.64%)was higher than that in the control group(70.45%,P<0.05),and the total effective rate in the observation group(86.36%)was higher than that in the control group(65.91%,P<0.05).Conclusion Hepatic artery infusion embolization combined with targeted nursing intervention in patients wi

关 键 词：原发性肝癌 肝动脉灌注栓塞术 癌性疲乏 对应性护理 临床疗效 护理满意度 

分 类 号：R473.73[医药卫生—护理学]