胰岛素泵连续皮下注射治疗糖尿病的临床疗效分析  

Analysis of Clinical Efficacy of Continuous Subcutaneous Injection of Insulin Pump in the Treatment of Diabetes

作　　者：郭吉璇 GUO Jixuan(Department of Endocrinology,Shantou Chaonan Minsheng Hospital,Shantou,Guangdong Province,515100 China)

机构地区：[1]汕头潮南民生医院内分泌科,广东汕头515100

出　　处：《糖尿病新世界》2022年第2期81-84,共4页Diabetes New World Magazine

摘　　要：目的评价胰岛素泵连续皮下注射用于糖尿病的临床治疗效果。方法选取该院2020年6月—2021年7月收治的130例糖尿病患者为研究对象,根据随机数表法的原则将其分为两组,对照组和观察组,各65例。对照组采用胰岛素皮下注射治疗,观察组采用胰岛素泵连续皮下注射治疗,比较两种治疗方法的临床疗效。结果观察组和对照组相比,治疗总有效率更高,差异有统计学意义(P<0.05);治疗后两组的空腹血糖、餐后2 h血糖、糖化血红蛋白与治疗前相比均明显降低,并且观察组治疗后血糖值显著低于对照组,差异有统计学意义(P<0.05);与对照组相比,观察组患者的血糖达标时间更短,胰岛素用量更少,差异有统计学意义(P<0.05);观察组的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05);观察组的低血糖发生率显著低于对照组,差异有统计学意义(P<0.05)。结论采用胰岛素泵连续皮下注射治疗糖尿病兼具有效性和安全性,可缩短血糖达标时间,平稳控糖,优势显著。Objective To evaluate the clinical treatment effect of continuous subcutaneous injection of insulin pump for diabetes.Methods 130 diabetic patients admitted to the hospital from June 2020 to July 2021 were selected as the study subjects.According to the principle of random number table method,they were divided into two groups,the control group and the observation group,with 65 cases in each group.The control group was treated with insulin subcutaneous injection,and the observation group was treated with continuous subcutaneous injection of insulin pump to compare the clinical efficacy of the two treatment methods.Results Compared with the control group,the total effective rate of the observation group was higher,and the difference was statistically significant(P<0.05).After treatment,the fasting blood glucose,postprandial 2 h blood glucose and glycosylated hemoglobin of the two groups were significantly lower than those before treatment,and the blood glucose value of the observation group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).Compared with the control group,the observation group had shorter blood glucose compliance time and less insulin dosage,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).The incidence of hypoglycemia in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The continuous subcutaneous injection of the insulin pump in the treatment of diabetes is both effective and safe,can shorten the time for blood glucose to reach the standard,and control the blood glucose steadily.It has significant advantages.

关 键 词：胰岛素泵连续皮下注射 胰岛素皮下注射 糖尿病 血糖值 临床疗效 不良反应 

分 类 号：R587.1[医药卫生—内分泌]