伏立康唑治疗新生儿侵袭性真菌感染的药学实践  

Pharmaceutical practice of voriconazole in the treatment of neonatal invasive fungal infection

作　　者：张莎莎[1] 李金纯 张雪丽 葛宁 王慧[1] ZHANG Sha-sha;LI Jin-chun;ZHANG Xue-li;GE Ning;WANG Hui(Maternal and Child Health Hospital of Hubei Province,Wuhan 430070,China)

机构地区：[1]湖北省妇幼保健院,湖北武汉430070

出　　处：《中国药物应用与监测》2022年第1期55-58,共4页Chinese Journal of Drug Application and Monitoring

摘　　要：目的:探讨临床药师对侵袭性真菌感染的新生儿实施药学服务的方法和意义。方法:临床药师参与2例侵袭性真菌感染新生儿的药物治疗,协助医师遴选适宜的抗真菌药物,确定给药剂量,监测伏立康唑血药浓度,关注药物相互作用和不良反应,为患儿提供全程药学服务。结果:医师采纳临床药师推荐方案进行治疗,患儿病情稳定好转,未出现明显药品不良反应,随访转归良好。结论:临床药师关注特定人群、特定病种的专科用药,选取恰当的药学服务切入点,可为患者提供个体化的药学服务,保障其用药安全有效。Objective:To explore the methods and significance of pharmaceutical care for neonates with invasive fungal infection by clinical pharmacists.Methods:Clinical pharmacists participated in the drug treatment of 2 neonates with invasive fungal infection,and assisted doctors in selecting appropriate antifungal drugs,determining the dosage,monitoring the blood concentration of voriconazole,paying attention to drug interactions and adverse reactions,and provided full pharmaceutical care for them.Results:Doctors adopted the scheme recommended by the clinical pharmacists.The patients'condition was stable and improved.There was no obvious adverse drug reaction.The follow-up results were good.Conclusion:Clinical pharmacists paid attention to the special medication of specific population and specific diseases,and select the appropriate entry point of pharmaceutical care,which could provide individualized pharmaceutical care for patients and ensure the safety and effectiveness of drug use.

关 键 词：侵袭性真菌感染 新生儿 药学服务 伏立康唑 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]