先天性色素痣的诊疗进展  

Update of diagnosis and treatment of congenital pigmented nevus

作　　者：陈见友 张高磊[1] 刘晓雁[1] CHEN Jianyou;ZHANG Gaolei;LIU Xiaoyan(Department of Dermatology,Children s Hospital,Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]首都儿科研究所附属儿童医院皮肤科,北京100020

出　　处：《中国麻风皮肤病杂志》2022年第5期338-342,共5页China Journal of Leprosy and Skin Diseases

基　　金：首都儿科研究所所级基金(编号:LCPY-2021-04)。

摘　　要：先天性色素痣又称为先天性黑素细胞痣,在出生时或出生后不久出现,并具有独特的临床和组织病理学特征。先天性色素痣根据尺寸可分为四类:小痣、中痣、大痣和巨痣。约1%的新生儿患有先天性色素痣,其中大多数属于小/中型痣,大/巨痣比较罕见。本文将从临床、并发症、病理、基因、治疗等多方面对先天性色素痣进行总结,以期提高临床诊疗水平。Congenital pigmented nevus,also known as congenital melanocytic nevus(CMN),appears at birth or shortly after birth and has unique clinical and histopathological characteristics.According to the size,congenital nevus can be divided into the following four types:small nevus,medium nevus,large nevus and giant nevus.It is estimated that about 1%of newborns have congenital nevi,most of which are small/medium nevi,and large/giant nevi are rare.This article summarizes the progress of congenital pigmented nevus from the aspects of clinical,complication,pathology,gene and treatment,in order to improve the level of clinical diagnosis and treatment.

关 键 词：先天性色素痣 NRAS BRAF 神经皮肤黑变病 黑素瘤 

分 类 号：R758.51[医药卫生—皮肤病学与性病学]