随机尿微量白蛋白肌酐比值在糖尿病肾损伤患者诊疗中的应用分析  

Application Analysis of Random Urine Microalbumin-creatinine Ratio in Diagnosis and Treatment of Diabetic Renal Injury Patients

作　　者：马艳 MA Yan(Beitaipingzhuang Community Health Service Center,Haidian District,Beijing,100082 China)

机构地区：[1]北京市海淀区北太平庄社区卫生服务中心,北京100082

出　　处：《糖尿病新世界》2022年第1期22-25,共4页Diabetes New World Magazine

摘　　要：目的分析糖尿病肾损伤患者诊疗中随机尿微量白蛋白肌酐比值的应用。方法回顾性选取2020年2月—2021年2月该院糖尿病患者90例为研究对象,依据肾损伤程度分为24 h尿白蛋白排泄率(UAER)<30 mg/24 h组(正常白蛋白尿组)、UAER 30~300 mg/24 h组(微量白蛋白尿组)、UAER>300 mg/24 h组(大量白蛋白尿组)。另回顾性选取同期该院健康体检人员30名作为健康对照组,统计分析4组人员的UmAlb、ACR水平,以及正常白蛋白尿组、微量白蛋白尿组及大量白蛋白尿组患者的UmAlb、ACR诊断阳性情况、治疗前后的UmAlb、ACR水平。结果正常白蛋白尿组、微量白蛋白尿组、大量白蛋白尿组患者的UmAlb、ACR水平均逐渐升高,组间差异有统计学意义(P<0.05),微量白蛋白尿组、大量白蛋白尿组患者的UmAlb、ACR水平均高于健康对照组,差异有统计学意义(P<0.05),正常白蛋白尿组患者的ACR高于健康对照组,差异有统计学意义(P<0.05),但正常白蛋白尿组和健康对照组人员的UmAlb水平比较,差异无统计学意义(P>0.05)。正常白蛋白尿组、微量白蛋白尿组、大量白蛋白尿组患者的UmAlb阳性率分别为6.67%(2/30)、90.00%(27/30)、100.00%(30/30),ACR阳性率分别为36.67%(11/30)、93.33%(28/30)、100.00%(30/30),组间差异有统计学意义(P<0.05)。3组患者治疗后的UmAlb、ACR水平均低于治疗前,差异有统计学意义(P<0.05);治疗前后,正常白蛋白尿组、微量白蛋白尿组、大量白蛋白尿组患者的UmAlb、ACR水平均逐渐升高,组间差异有统计学意义(P<0.05)。结论糖尿病肾损伤患者诊疗中随机尿微量白蛋白肌酐比值的应用价值高。Objective To analyze the application of random urine microalbumin-creatinine ratio in the diagnosis and treatment of diabetic kidney injury patients. Methods From February 2020 to February 2021, 90 diabetic patients in the hospital were retrospectively selected as the research objects. According to the degree of kidney injury, they were divided into 24 h urinary albumin excretion rate(UAER) <30 mg/24 h group(normal albuminuria group),UAER 30-300 mg/24 h group(microalbuminuria group), UAER>300 mg/24 h group(major albuminuria group). In addition, a retrospective selection of 30 health examiners in the hospital during the same period was used as the healthy control group, and the UmAlb and ACR levels of the 4 groups were statistically analyzed, as well as the positive diagnosis of UmAlb and ACR, and the UmAlb levels and ACR before and after treatment normal albuminuriagroup, microalbuminuria group, major albuminuria group. Results The UmAlb and ACR levels of patients in the normal albuminuria group, microalbuminuria group, and macroalbuminuria group gradually increased,and the difference between the groups was statistically significant(P <0.05). Microalbuminuria group and macroalbuminuria group the UmAlb and ACR levels were higher than those of the healthy control group, and the difference was statistically significant(P<0.05). The ACR of the normal albuminuria group was higher than that of the healthy control group, and the difference was statistically significant(P <0.05), but there was no statistically significant difference in the UmAlb level between the normal albuminuria group and the healthy control group(P>0.05). The positive rates of UmAlb in the normal albuminuria group, microalbuminuria group, and macroalbuminuria group were 6.67%(2/30), 90.00%(27/30), 100.00%(30/30), and the positive rates of ACR were 36.67%(11/30),93.33%(28/30), 100.00%(30/30), and the difference between the groups was statistically significant(P<0.05). UmAlb and ACR levels of the three groups of patients after treatment were lower than

关 键 词：糖尿病 肾损伤 24 h尿白蛋白排泄率 白蛋白尿 随机尿微量白蛋白肌酐比值 

分 类 号：R587.1[医药卫生—内分泌]