新型敷料在2型糖尿病足溃疡伴多重耐药菌感染中的临床应用  

Clinical Application of New Dressings in Type 2 Diabetic Foot Ulcers with Multi-drug Resistant Bacteria Infection

作　　者：栾淼 LUAN Miao(Department of Nosocomial Infection Management,Changchun Central Hospital,Changchun,Jilin Province,130051 China)

机构地区：[1]长春市中心医院医院感染管理科,吉林长春130051

出　　处：《糖尿病新世界》2022年第1期176-179,共4页Diabetes New World Magazine

摘　　要：目的分析2型糖尿病足溃疡伴多重耐药菌感染患者应用新型敷料的疗效。方法选择2018年1月—2021年1月在该院进行临床治疗的60例2型糖尿病足溃疡伴多重耐药菌感染患者,基于奇偶数分组法将其划分为对照组和研究组,每组30例。对照组借助传统敷料对患者施以治疗,研究组应用新型敷料对患者施以治疗。对两组患者临床治疗效果进行比较。结果研究组患者治疗5 d和15 d溃疡面积分别为(312.29±4.79)mm;、(185.97±3.05)mm^(2),优于对照组,差异有统计学意义(t=38.968、114.067,P<0.001);治疗后,研究组患者空腹血糖、糖化血红蛋白、肿瘤坏死因子-α(TNF-α)以及C反应蛋白(CRP)为(9.46±2.08)mmol/L、(7.34±2.08)%、(14.26±3.02)pg/L、(6.73±2.97)mg/L,均优于对照组,差异有统计学意义(t=2.667、2.252、4.790、3.110,P<0.05);研究组患者临床溃疡愈合率为93.3%,显著高于对照组,差异有统计学意义(χ^(2)=4.007,P=0.045)。结论应用新型敷料对2型糖尿病足溃疡伴多重耐药菌感染患者施以治疗可以改善患者血糖水平,促进患者溃疡面积的愈合,降低炎症因子水平,值得研究推广。Objective To analyze the efficacy of new dressings in patients with type 2 diabetic foot ulcers and multi-drug resistant bacteria infections. Methods From January 2018 to January 2021, 60 patients with type 2 diabetic foot ulcer complicated with multidrug-resistant bacterial infection were selected and divided into control group and study group based on odd-even grouping method, with 30 patients in each group. Patients in the control group were treated with a traditional dressing, and patients in the study group were treated with a new dressing. The clinical treatment effect was compared between the two groups. Results The ulcer area of patients in the study group was(312.29±4.79) mm;and(185.97±3.05) mm;at 5 d and 15 d after treatment, which was better than that in the control group, and the difference was statistically significant(t=38.968, 114.067, P<0.001). After treatment, fasting blood glucose, glycosylated hemoglobin, TUMOR necrosis factor-α(TNF-α) and C-reactive protein(CRP) in study group were(9.46±2.08) mmol/L,(7.34±2.08) %,(14.26±3.02) pg/L,(6.73±2.97) mg/L, which were better than those in control group. The difference was statistically significant(t =2.667, 2.252, 4.790, 3.110, P <0.05). The clinical ulcer healing rate of patients in the study group was 93.3%, which was significantly higher than that in the control group. The difference was statistically significant(χ^(2)=4.007, P=0.045). Conclusion The use of new dressings to treat patients with type 2 diabetic foot ulcers with multi-drug resistant bacteria infection can improve blood glucose levels in patients. Promote the healing of the ulcer area of patients and reduce the level of inflammatory factors, which is worthy of research and promotion.

关 键 词：新型敷料 2型糖尿病足溃疡 多重耐药菌感染 溃疡面积 血糖水平 

分 类 号：R59[医药卫生—内科学]