含铜宫内节育器与米非司酮用于紧急避孕临床对比研究  

Clinical Comparative study on the Use of Copper-containing Intrauterine Device and Mifepristone for Emergency Contraception

作　　者：王宜芹 王宏雁 WANG Yiqin;WANG Hongyan(Department of Medicine Management Service,Rizhao Center for Disease Control and Prevention,Rizhao,Shandong Province,276800 China;Wolongshan Community Health Service Center,Shanhaitian Tourist Resort,Rizhao,Shandong Province,276800 China)

机构地区：[1]日照市疾病预防控制中心药具管理服务科,山东日照276800 [2]日照市山海天旅游度假区卧龙山社区卫生服务中心,山东日照276800

出　　处：《世界复合医学》2021年第12期40-43,共4页World Journal of Complex Medicine

摘　　要：目的比较含铜宫内节育器、米非司酮在紧急避孕中的临床运用效果。方法抽取2020年10月—2021年9月该院接诊的需紧急避孕的90名女性作为研究对象,按其自愿选择的避孕方式,均分成甲组与乙组,每组各有45名女性;甲组采取含铜宫内节育器进行避孕,乙组采取米非司酮进行避孕。对上述两组女性的紧急避孕效果情况进行观察与比较。结果甲组中有44名女性紧急避孕成功,1名失败,其成功率为97.78%(44/45);乙组中有43名女性紧急避孕成功,2名失败,其成功率为95.56%(43/45),组间紧急避孕成功率比较,差异无统计学意义(χ^(2)=0.000,P>0.05);甲组中共有18名女性发生月经改变,其发生率为40.00%,乙组中共有14名女性发生月经改变,其发生率为31.11%,两组女性的月经改变率比较,差异无统计学意义(χ^(2)=0.778,P>0.05);甲组中共有5名女性发生不良反应,其发生率为11.11%,乙组中共有7名女性发生不良反应,其发生率为15.56%,两组女性的不良反应发生率比较,差异无统计学意义(χ^(2)=0.385,P>0.05)。结论含铜宫内节育器、米非司酮两者在女性紧急避孕中均可获得较好的效果,女性可依据自身实际情况,选择最为合适的避孕方式。Objective To compare the clinical effects of copper-containing intrauterine devices and mifepristone in emergency contraception.Methods A total of 90 women in need of emergency contraception who were admitted to the hospital from October 2020 to September 2021 were selected as the subjects of study.According to the contraceptive methods they choose voluntarily,they were divided into group A and group B,with 45 women in each group.Group A took a copper-containing intrauterine device for contraception,and group B took mifepristone for contraception.Observed and compared the emergency contraceptive effect of the above two groups of women.Results After treatment analysis,44 women in group A succeeded in emergency contraception,and 1 failed,and the success rate was 97.78%(44/45);in group B,43 women in group B succeeded in emergency contraception,and 2 failed,and their success rate was 95.56%(43/45);there was no statistically significant difference in the success rate of emergency contraception between the groups(χ^(2)=0.000,P>0.05).A total of 18 women in group A had menstrual changes,with an incidence of 40.00%,and a total of 14 women in group B had menstrual changes,with an incidence of 31.11%;there was no statistically significant difference in the menstrual change rates of the two groups of women(χ^(2)=0.778,P>0.05).A total of 5 women in group A had adverse reactions,with an incidence rate of 11.11%,and a total of 7 women in group B had adverse reactions,with an incidence of 15.56%;there was no statistically significant difference in the incidence of adverse reactions between the two groups of women(χ^(2)=0.385,P>0.05).Conclusion Both the copper-containing intrauterine device and mifepristone can achieve better results in female emergency contraception.Women can choose the most suitable method of contraception based on their actual situation.

关 键 词：紧急避孕 含铜宫内节育器 米非司酮 不良反应 临床效果 

分 类 号：R4[医药卫生—临床医学]