桥本氏甲状腺炎与甲状腺乳头状癌相关性的研究进展  

Progress of Research on the Correlation between Hashimoto’s Thyroiditis and Papillary Thyroid Carcinoma

作　　者：陈如馨 陈万志[1] Chen Ruxin;Chen Wanzhi(Department of Thyroid Surgery,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi,China)

机构地区：[1]南昌大学第二附属医院甲状腺外科,南昌330006

出　　处：《肿瘤预防与治疗》2022年第2期186-193,共8页Journal of Cancer Control And Treatment

基　　金：国家自然科学基金(编号:81760320)。

摘　　要：桥本氏甲状腺炎(Hashimoto’sthyroiditis,HT)是一种内分泌系统的自身免疫性疾病,又称慢性淋巴细胞性甲状腺炎。甲状腺乳头状癌(papillary thyroid carcinoma,PTC)是甲状腺癌中发病率最高的一类肿瘤。近年来,PTC合并HT的发病率越来越高,引起了研究人员对两者之间关系进行多方面多角度的探索。虽然关于HT与PTC的研究众多,但许多方面仍具有争议性。本综述从流行病学相关性、发病机制研究、临床特征、预后及治疗等多角度阐述HT合并PTC的研究进展,为HT合并PTC的诊治提供理论基础,同时为未来HT与PTC的相关研究提供方向。Hashimoto*s thyroiditis(HT),also known as chronic lymphocytic thyroiditis,is an autoimmune disease of the endocrine system.Papillary thyroid carcinoma(PTC)is the most common type of thyroid cancer,with the highest incidence in all thyroid cancers.The relationship between PTC and HT has been exploring in many aspects for the increasing incidence of PTC combined with HT in recent years,the results are controversial though.This review expounds the progress of research on HT combined with PTC in terms of pathogenesis,clinical features,prognosis,treatment and their correlation in epidemiology,in order to offer theoretical basis for the diagnosis and treatment of HT and PTC,and direct future research on them.

关 键 词：桥本甲状腺炎 甲状腺乳头状癌 流行病学 发病机制 免疫治疗 

分 类 号：R581.4[医药卫生—内分泌] R736.1[医药卫生—内科学]