甲巯咪唑致关节炎综合征一例  

One Case of Arthritis Syndrome Caused by Methimazole

作　　者：刘清 石绮屏[1] LIU Qing;SHI Qi-ping(Department of Endocrinology,The First Affiliated Hospital of Ji’nan University,Guangzhou,Guangdong,510630,China)

机构地区：[1]暨南大学附属第一医院内分泌科,广东广州510630

出　　处：《黑龙江医学》2022年第4期455-456,459,共3页Heilongjiang Medical Journal

基　　金：国家自然科学基金青年科学基金项目(31500742,2015A030313312)。

摘　　要：由于甲状腺腺体本身功能亢进,合成和分泌甲状腺激素增加所导致的甲状腺毒症称为甲状腺功能亢进症(简称甲亢)。抗甲状腺药物(Antithyroid Drugs,ATD)是治疗甲亢的常用方法之一,其常见副作用是皮疹、粒细胞缺乏症、中毒性肝病、血管炎,但ATD关节炎综合征少见。本文报道1例以ATD关节炎综合征为副作用的甲亢患者的诊治及随访过程,以期为临床治疗提供诊断、治疗提供依据。Thyrotoxicosis caused by the increased synthesis and secretion of thyroid hormones is called hyperthyroidism(referred to as hyperthyroidism)due to the hyperfunction of the thyroid gland itself.Antithyroid Drugs(ATD)is one of the commonly used methods for the treatment of hyperthyroidism.The common side effects are skin rash,agranulocytosis,toxic liver disease,and vasculitis,but ATD arthritis syndrome is rare.The article reports the diagnosis,treatment and follow-up of a case of hyperthyroidism with ATD arthritis syndrome as a side effect,in order to provide a basis for diagnosis and treatment of clinical treatment.

关 键 词：甲巯咪唑 抗甲状腺药物 关节炎综合征 

分 类 号：R581[医药卫生—内分泌]