杭州市呼吸道合胞病毒引起幼儿园急性呼吸道感染暴发疫情调查  

Investigation on outbreaks of acute respiratory tract infection caused by respiratory syncytial virus in kindergartens in Hangzhou

作　　者：杨旭辉[1] 于新芬[2] 张晨烨 王芬 朱雷 蒋龙芳[4] 王婧[1] 刘牧文[1] YANG Xuhui;YU Xinfen;ZHANG Chenye;WANG Fen;ZHU Lei;JIANG Longfang;WANG Jing;LIU Muwen(不详;Infectious Disease Prevention and Control Institute,Hangzhou Center for Disease Control and Prevention,Hangzhou(31002l),China)

机构地区：[1]浙江省杭州市疾病预防控制中心传染病防制所,310021 [2]杭州市疾病预防控制中心卫生检验中心 [3]杭州市拱墅区疾病预防控制中心传防科 [4]杭州市萧山区疾病预防控制中心传防所

出　　处：《中国学校卫生》2022年第1期142-145,共4页Chinese Journal of School Health

基　　金：杭州市医药卫生科技项目(A20200591)。

摘　　要：目的分析呼吸道合胞病毒感染引起的儿童急性呼吸道感染暴发疫情的特点,并对防控工作予以总结和评价,为集体单位呼吸道感染暴发疫情防控提供依据。方法采用现场流行病学调查的方法对杭州市两起疫情进行调查,采用描述流行病学的方法对资料进行分析;采用PCR方法对标本进行检测,并对呼吸道合胞病毒核酸阳性的标本进行测序。结果两起疫情均发生在幼儿园,A幼儿园发病21例,持续11 d,B幼儿园发病43例,持续33 d,流行曲线呈现增殖模式。病例集中在托班和小班,年龄2~4岁为主。症状以发热、咳嗽为主,主要为上呼吸道感染,未发现重症病例。采集病例上呼吸道标本检测,为呼吸道合胞病毒阳性,对4份标本进行测序,为B亚群。结论幼儿园急性呼吸道感染暴发时要考虑呼吸道合胞病毒,注意与其他呼吸道感染引起的暴发疫情的鉴别,控制措施要严格,避免疫情长久持续。Objective In order to analyze the characteristics of the outbreak of acute respiratory tract infection in children caused by respiratory syncytial virus(RSV).Methods The field epidemiological investigations were conducted for the two outbreaks in kindergartens in Hangzhou.Data were analyzed by descriptive method.Samples with positive respiratory syncytial virus nucleic acid were sequenced using PCR.Results The two outbreaks occurred in kindergartens.There were 21 cases in kindergarten A,lasting 11 days,and 43 cases in kindergarten B,lasting 33 days.The epidemic curve showed a proliferation pattern.The cases were concentrated in nurseries and K1 classes,primarily among children aged 2-4 years.The most common symptoms were fever and cough,mainly upper respiratory tract infection,and no severe cases were found.Upper respiratory tract samples were collected and detected as positive for RSV.Four samples were sequenced and identified as subgroup B.Conclusion During the outbreak of acute respiratory infection in kindergartens,respiratory syncytial virus should be given primary consideration in the process of identification of the outbreak caused by other respiratory infections,and strictly control measures should be taken to reduce the long-term impact of the epidemic.

关 键 词：呼吸道合胞病毒 呼吸道感染 疾病暴发流行 儿童 

分 类 号：R183[医药卫生—流行病学] R181.3[医药卫生—公共卫生与预防医学]