呼吸道黏膜免疫和呼吸道黏膜疫苗研究进展  

Respiratory mucosal immunity and advances of respiratory mucosal vaccine research

作　　者：尹一凡 林敏 强宏生 郑子峥[1] Yin Yifan;Lin Min;Qiang Hongsheng;Zheng Zizheng(State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics,Xiamen University/National Institute of Diagnostics and Vaccine Development in Infectious Diseases,Xiamen University/School of Public Health,Xiamen University,Xiamen 361102,Fujian,China)

机构地区：[1]厦门大学分子疫苗学与分子诊断学国家重点实验室/国家传染病诊断试剂与疫苗工程技术研究中心/厦门大学公共卫生学院,福建厦门361102

出　　处：《中国疫苗和免疫》2022年第1期121-127,共7页Chinese Journal of Vaccines and Immunization

摘　　要：呼吸道黏膜免疫系统是机体抵御空气传播病原体的第一道防线。本文总结了黏膜免疫相关的呼吸道黏膜上皮细胞组成和局部黏膜免疫应答过程,探讨了黏膜免疫的优势和呼吸道黏膜疫苗研发面临的挑战。The respiratory mucosal immune system serves as the first line of defense against airborne pathogens.In this review,we summarize the composition of respiratory mucosal epithelial cells associated with mucosal immunity and the process of the local mucosal immune response.We describe advantages of mucosal immunity and challenges for respiratory mucosal vaccine research.

关 键 词：呼吸道黏膜 黏膜免疫 呼吸道黏膜疫苗 

分 类 号：R392[医药卫生—免疫学]