毯式光纤黄疸治疗仪联合布拉氏酵母菌治疗新生儿黄疸的临床效果  

Clinical effect of blanket light jaundice therapeutic instrument combined with saccharomyces boulardii in the treatment of neonatal jaundice

作　　者：朱莉莉 周俊霞 张利敏[1] 赵晓卫[1] 王庆敏 王东英 ZHU Lili;ZHOU Junxia;ZHANG Limin;ZHAO Xiaowei;WANG Qingmin;WANG Dongying(Neonatology Department,the 7th People's Hospital of Zhengzhou,Zhengzhou 450004,China)

机构地区：[1]郑州市第七人民医院新生儿科,河南郑州450004

出　　处：《临床医学研究与实践》2022年第7期98-101,共4页Clinical Research and Practice

摘　　要：目的探究毯式光纤黄疸治疗仪联合布拉氏酵母菌治疗新生儿黄疸的临床效果。方法选取我院2019年5月至2020年5月收治的100例新生儿黄疸患儿作为研究对象,随机将其分为对照组和试验组,各50例。对照组给予常规治疗联合布拉氏酵母菌治疗,试验组在对照组基础上给予毯式光纤黄疸治疗仪治疗。比较两组患儿的血清胆红素水平、黄疸指数、症状恢复时间、免疫功能指标及不良反应发生情况。结果治疗后72、120 h,试验组的血清胆红素水平明显低于对照组(P<0.05)。治疗后,试验组的黄疸指数明显低于对照组(P<0.05)。试验组的第一次排胎便时间、胎便转黄时间及黄疸消退时间均明显短于对照组(P<0.05)。治疗后,两组的CRP水平均低于治疗前,TRF水平及RFEF、RBC-C3bR均高于治疗前,且试验组优于对照组(P<0.05)。试验组的不良反应总发生率为4.00%,明显低于对照组的14.00%,差异具有统计学意义(P<0.05)。结论毯式光纤黄疸治疗仪联合布拉氏酵母菌在新生儿黄疸治疗中具有较好的作用,有助于患儿黄疸快速消退,增强免疫功能,且安全性较高,值得在临床积极推广。Objective To explore the clinical effect of blanket light jaundice therapeutic instrument combined with saccharomyces boulardii in the treatment of neonatal jaundice.Methods A total of 100 children with neonatal jaundice treated in our hospital from May 2019 to May 2020 were selected as the research objects,and the children were randomly divided into control group and experimental group,with 50 cases in each group.The control group was treated with routine treatment combined with saccharomyces boulardii,and the experimental group was treated with blanket light jaundice therapeutic instrument on the basis of the control group.The serum bilirubin level,jaundice index,symptom recovery time,immune function indexes and occurrence of adverse reactions were compared between the two groups.Results At 72 and 120 h after treatment,the level of serum bilirubin in the experimental group was significantly lower than that in the control group(P<0.05).After treatment,the jaundice index of the experimental group was significantly lower than that of the control group(P<0.05).The first defecation time,the time of fetal stool turning yellow and the time of jaundice regression in the experimental group were significantly shorter than those in the control group(P<0.05).After treatment,the CRP level in the two groups was lower than that before treatment,and the TRF level,RFEF and RBC-C3bR were higher than those before treatment,and those in the experimental group were better than the control group(P<0.05).The total incidence of adverse reactions in the experimental group was 4.00%,which was significantly lower than 14.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Blanket light jaundice therapeutic instrument combined with saccharomyces boulardii plays a good role in the treatment of neonatal jaundice,which is helpful for the rapid regression of jaundice in children,enhance immune function,and has high safety.It is worthy of active promotion in clinical.

关 键 词：新生儿黄疸 毯式光纤黄疸治疗仪 布拉氏酵母菌 胆红素 黄疸指数 免疫功能 

分 类 号：R473.72[医药卫生—护理学]