自体腹膜补片修补缺损血管的研究进展  

Research progress of autologous peritioneal patch for repairing defective blood vessels

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作  者:隋晓军 张大鹏[1] 钟玉川[1] 孙向宇[1] Sui Xiaojun;Zhang Dapeng;Zhong Yuchuan;Sun Xiangyu(Department of Hepatobiliary and Pancreatic Surgery,TianJin Nankai Hospital,Tianjin 300100,China)

机构地区:[1]天津市南开医院肝胆胰外科,天津300100

出  处:《中华肝胆外科杂志》2022年第2期157-160,共4页Chinese Journal of Hepatobiliary Surgery

摘  要:在进行腹腔恶性肿瘤根治性切除手术的过程中,经常会遇到大血管受侵犯的情况,这不但给手术增加了难度,也直接影响到了根治效果和预后。随着联合血管切除重建的扩大根治性手术相关技术的发展,外科医师开始采用自体、异体或者人工血管进行术中缺损血管修补,从而达到根治性手术的效果。但由于这些材料都有不足之处,所以学者们一直在寻求更好的替代物。鉴于腹膜间皮细胞与血管内皮细胞在胚胎学、组织学和生理学方面有许多相似之处,且腹膜组织相较于自体、异体或者人工血管更容易获取,将自体腹膜制作成补片来修补缺损血管在理论和技术上具有可行性。本文就目前自体腹膜补片修补缺损血管的研究进展作一综述。In the process of radical resection of abdominal malignant tumors,large blood vessels are often invaded,which not only increases the difficulty of operation,but also directly affects the curative effect and prognosis.As the concept of expanded radical surgery combined with vascular resection and reconstruction and related techniques have been gradually recognized,surgeons have begun to use autologous,allogeneic or artificial vessels to repair the defective blood vessels during surgery,so as to achieve the effect of radical surgery.However,due to the short comings of these materials,scholars have been looking for better alternatives.In view of the fact that the mesothelial cells of the peritoneum and the endothelial cells of the blood vessels have many similarities in embryology,histology and physiology,and peritoneum is also easier to obtain than autologous,allogeneic or artificial vessels.To make the autologous peritoneum into a patch for repairing the defective blood vessels is feasible in theoretical and technical.In this paper,we review the current research progress of autologous peritoneal patch to repair blood vessels of defect.

关 键 词:腹膜 移植 自体 间皮细胞 内皮细胞 血管重建 

分 类 号:R730.56[医药卫生—肿瘤]

 

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