Non-canonical role of the ATR pathway in axon regeneration as a mechanosensitive brake  

作　　者：Feng Li Yuanquan Song 

机构地区：[1]Institute for Translational Brain Research,Fudan University,Shanghai,China [2]Raymond G.Perelman Center for Cellular and Molecular Therapeutics,The Children’s Hospital of Philadelphia,and Department of Pathology and Laboratory Medicine,University of Pennsylvania,Philadelphia,PA,USA

出　　处：《Neural Regeneration Research》2022年第11期2423-2424,共2页中国神经再生研究（英文版）

基　　金：the National Institutes of Health Grant,1R01NS107392(to YS).

摘　　要：DNA damage has been linked to neuropathology.Diverse DNA damage response(DDR)pathways help preserve DNA integrity in the nervous system during both the developmental and mature stages.Mutations of factors in various signaling pathways responsive to different types of DNA damage have been associated with developmental syndromes with neurological symptoms(McKinnon,2009;Araújo and Kuraoka,2019;Khokhlova et al.,2020).

关 键 词：damage ATR DDR 

分 类 号：R338[医药卫生—人体生理学]