超声造影对膀胱占位性病变的诊断及相关分析  

Diagnosis and Correlation Analysis of Bladder Space Occupying Lesions by Contrast-enhanced Ultrasound

作　　者：李峰 邵继春 杨剑波 石波 LI Feng;SHAO Jichun;YANG Jianbo;SHI Bo(The Second Affiliated Hospital of Chengdu Medical College(China National Nuclear Corporation 416 Hospital),Chengdu 610051,Sichuan,P.R.China)

机构地区：[1]成都医学院第二附属医院(核工业四一六医院),四川成都610051

出　　处：《影像科学与光化学》2022年第2期372-376,共5页Imaging Science and Photochemistry

基　　金：成都市卫生健康委员会医学科研课题(2018065)。

摘　　要：本研究探讨超声造影(CEUS)应用于膀胱占位性病变良恶性鉴别的价值。以82例膀胱占位性病变患者为研究对象,病灶共计105个,比较良、恶性病灶超声造影参数差异,包括到达时间(AT)、达峰时间(TTP)、峰值强度(PI)和廓清时间(WT)。结果显示,术后病理确诊恶性病灶61个,超声造影诊断膀胱恶性病变的灵敏性为90.16%、特异性为90.91%、准确性为90.48%;高级别恶性病灶的PI和WT值明显高于低级别病灶(P<0.05);T分期≥T3分期病灶PI和WT明显高于Ta-1和T2期病灶(P<0.05);PI、WT预测高级别病灶的ROC曲线下面积分别为0.712和0.888;PI、WT预测T分期≥T3病灶的ROC曲线下面积分别为0.812和0.852。超声造影诊断膀胱占位性病变价值高,值得临床使用。This study explored the value of contrast-enhanced ultrasound(CEUS) in the differentiation of benign and malignant bladder occupying lesions. Eighty-two patients with space-occupying bladder lesions were selected as the research object, there were a total of 105 lesions. The differences of contrast-enhanced ultrasound parameters between benign and malignant lesions were compared, including time to arrival(AT), time to peak(TTP), peak intensity(PI) and washout time(WT). The results showed that 61 malignant lesions were confirmed pathologically after operation, and the sensitivity, specificity and accuracy of CEUS in diagnosing malignant bladder lesions were 90.16%, 90.91% and 90.48% respectively. PI and WT values of the high-grade malignant lesions were significantly higher than those of the low-grade malignant lesions(P<0.05). The PI and WT of T stage≥T3 lesions were significantly higher than those of Ta-1 and T2 lesions(P<0.05). The areas under the ROC curve of PI and WT for predicting high-grade lesions were 0.712 and 0.888, respectively. The areas under the ROC curve of PI and WT in predicting T stage ≥ T3 lesions were 0.812 and 0.852, respectively. CEUS is of high value in the diagnosis of bladder space occupying lesions, preoperative T staging and pathological grading, and is worthy of clinical use.

关 键 词：超声造影 膀胱占位性病变 T分期 病理分级 诊断价值 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.14[医药卫生—诊断学]